Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 6/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30526816 | 0.75 | MAPT (0.56) | ALOX15PIM1RAB9ANPC1TP53 | |
| SCHEMBL15079503 | 0.75 | MAPT (0.56) | ALOX15PIM1RAB9ANPC1TP53 | |
| SCHEMBL12557899 | 0.75 | MAOB (0.46) | ALDH1A1KDM4EHPGDTSHRHTT | |
| Hydrochloric Acid SCHEMBL4875256 | 0.74 | HDAC6 (0.43) | ALDH1A1KDM4EHPGDHTTHSD17B10 | |
| Hydrochloric Acid SCHEMBL4875252 | 0.73 | HDAC6 (0.42) | ALDH1A1KDM4EHPGDHTTKMT2A | |
| SCHEMBL31452300 | 0.70 | WNT3A (0.44) | KDM4EKMT2AMAPT | |
| SCHEMBL2743511 | 0.68 | LRRK2 (0.55) | ALDH1A1KDM4EHPGDSMN1; SMN2MAPT | |
| SCHEMBL1979808 | 0.68 | GAA (0.42) | ALDH1A1KDM4EHPGDHTTHSD17B10 | |
| SCHEMBL21997986 | 0.67 | PKM (0.53) | ALDH1A1KDM4EHPGDHTTPOLB | |
| SCHEMBL1981584 | 0.67 | GAA (0.41) | ALDH1A1KDM4EHPGDTSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709480-A1 | 5,6-FUSED BICYCLIC AMIDES AND COMPOSITIONS FOR USE AS 15-PROSTAGLANDIN DEHYDROGENASE MODULATORS | Amgen Inc. (US) | 2026-03-18 | — | — | EP | claimed |
| EP-4709480-A1 | 5,6-FUSED BICYCLIC AMIDES AND COMPOSITIONS FOR USE AS 15-PROSTAGLANDIN DEHYDROGENASE MODULATORS | Amgen Inc. (US) | 2026-03-18 | — | — | EP | disclosed |