SCHEMBL32686327

SCHEMBL32686327

O=S(=O)(OCCOC(F)F)C(F)(F)F

nearest known ligand 0.42

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.42
CA1 P00915 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29211261 0.83 CA2 (0.37) CA2CA1
SCHEMBL1032931 0.83 CA2 (0.47) CA2CA1
SCHEMBL17629780 0.81 CA2 (0.38) CA2CA1
SCHEMBL4953881 0.77 CA2 (0.43) CA2CA1
SCHEMBL4949086 0.77 CA2 (0.43) CA2CA1
SCHEMBL4949681 0.77 CA2 (0.43) CA2CA1
SCHEMBL8769681 0.76 CA1 (0.36) CA2CA1
SCHEMBL9148546 0.76 CA1 (0.34) CA2CA1
SCHEMBL24362707 0.76 CA2 (0.40) CA2CA1
SCHEMBL1455725 0.75 CA2 (0.32) CA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709718-A1 6-SUBSTITUTED-3-PHENYL-ISOINDOLIN-1-ONES AS CBL-B INHIBITORS SELECTIVE OVER C-CBL Genentech Inc. (US) 2026-03-18 EP disclosed