SCHEMBL8769681

SCHEMBL8769681

CCCCOC(C)OCCOS(=O)(=O)C(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA1 P00915 11/20 0.36
CA2 P00918 11/20 0.36
EPHX1 P07099 1/20 0.32
CA9 Q16790 8/20 0.32
CA12 O43570 3/20 0.31
CA7 P43166 3/20 0.31
CA14 Q9ULX7 3/20 0.31
CA3 P07451 2/20 0.31
CA4 P22748 2/20 0.31
CA6 P23280 2/20 0.31
CA5A P35218 2/20 0.31
CA5B Q9Y2D0 2/20 0.31
RECQL P46063 2/20 0.30
GLA P06280 1/20 0.30
HPGD P15428 1/20 0.30
TSHR P16473 1/20 0.30
MAPK1 P28482 1/20 0.30
EPHX2 P34913 1/20 0.30
BLM P54132 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28048576 0.86 LMNA (0.43) CA1CA2
SCHEMBL777643 0.82 CA2 (0.52) CA1CA2EPHX1CA9CA12
SCHEMBL27912318 0.80 CA1 (0.50) CA1CA2EPHX1CA9CA12
SCHEMBL27930318 0.80 CA1 (0.50) CA1CA2EPHX1CA9CA12
Fluoride SCHEMBL27893472 0.80 CA1 (0.50) CA1CA2EPHX1CA9CA12
SCHEMBL29170929 0.80 CA1 (0.50) CA1CA2EPHX1CA9CA12
SCHEMBL15744637 0.79 TSHR (0.42) CA1CA2EPHX1CA9CA12
SCHEMBL28206674 0.79 TSHR (0.42) CA1CA2EPHX1CA9CA12
SCHEMBL8769673 0.79 TSHR (0.42) CA1CA2EPHX1CA9CA12
SCHEMBL8769669 0.79 CA1 (0.32) CA1CA2EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0792255-A1 LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-09-03 EP disclosed