Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
| ▸ | CLK2 | P49760 | 1/20 | 0.36 |
| ▸ | CLK3 | P49761 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 3/20 | 0.35 |
| ▸ | MST1R | Q04912 | 2/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32686477 | 0.85 | CLK1 (0.35) | CLK1CLK2CLK3CDK5DYRK1A | |
| SCHEMBL27086356 | 0.81 | GRM2 (0.42) | ALDH1A1CDK5DYRK1ACLK4PIM1 | |
| SCHEMBL30004086 | 0.81 | GRM2 (0.42) | ALDH1A1CDK5DYRK1ACLK4PIM1 | |
| SCHEMBL25415363 | 0.79 | CDK5 (0.50) | CDK5DYRK1ACLK4PIM1CSNK1A1 | |
| SCHEMBL30598935 | 0.79 | CDK5 (0.50) | CDK5DYRK1ACLK4PIM1CSNK1A1 | |
| SCHEMBL11346836 | 0.78 | MEN1 (0.44) | CLK1CLK2CLK3CDK5DYRK1A | |
| SCHEMBL29920437 | 0.76 | ALDH1A1 (0.42) | ALDH1A1PIM1KDRGSK3BALDH1A3 | |
| SCHEMBL30598890 | 0.76 | GRM2 (0.35) | CDK5DYRK1ACLK4PIM1CSNK1A1 | |
| SCHEMBL21200740 | 0.76 | GRM2 (0.35) | CDK5DYRK1ACLK4PIM1CSNK1A1 | |
| SCHEMBL30605858 | 0.76 | GRM2 (0.38) | CDK5DYRK1ACLK4PIM1CSNK1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709718-A1 | 6-SUBSTITUTED-3-PHENYL-ISOINDOLIN-1-ONES AS CBL-B INHIBITORS SELECTIVE OVER C-CBL | Genentech Inc. (US) | 2026-03-18 | — | — | EP | disclosed |