Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 10/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3268666 | 1.00 | CTSK (0.45) | CTSKCA1CA2CA7CYP2D6 | |
| SCHEMBL3268668 | 0.81 | CA1 (0.46) | CTSKCA1CA2CA7CYP2D6 | |
| SCHEMBL13618660 | 0.78 | CA1 (0.50) | CTSKCA1CA2CA7CYP2D6 | |
| SCHEMBL13050322 | 0.78 | CA1 (0.50) | CTSKCA1CA2CA7CYP2D6 | |
| SCHEMBL15081362 | 0.78 | CA1 (0.50) | CTSKCA1CA2CA7CYP2D6 | |
| SCHEMBL963465 | 0.74 | CTSK (0.53) | CTSKCA1CA2CA7CYP2D6 | |
| SCHEMBL6422715 | 0.74 | CA1 (0.50) | CTSKCA1CA2CA7CYP2D6 | |
| SCHEMBL2058674 | 0.74 | CTSK (0.53) | CTSKCA1CA2CA7CYP2D6 | |
| SCHEMBL327825 | 0.74 | CTSK (0.53) | CTSKCA1CA2CA7CYP2D6 | |
| SCHEMBL375811 | 0.74 | CA1 (0.53) | CTSKCA1CA2CA7CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100286024-A1 | Insulinotropic compounds and uses thereof | ACTIVOTEC SPP LIMITED (GB) | 2010-11-11 | — | — | US | disclosed |
| EP-1943275-B1 | INSULINOTROPIC COMPOUNDS AND USES THEREOF | ACTIVOTEC SPP LTD (GB) | 2010-06-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286024-A1 | Insulinotropic compounds and uses thereof | GLP1R, GPR119, IAPP | CTSK 3336/4885CA1 3587/4885CA2 2582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.