Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTC4S | Q16873 | 15/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PLK1 | P53350 | 2/20 | 0.45 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2755442 | 0.93 | LTC4S (0.62) | LTC4S | |
| SCHEMBL2755444 | 0.87 | LTC4S (0.61) | LTC4SMETAP2 | |
| SCHEMBL2755445 | 0.83 | LTC4S (0.63) | LTC4S | |
| SCHEMBL239329 | 0.80 | LTC4S (0.65) | LTC4S | |
| SCHEMBL251507 | 0.77 | LTC4S (0.71) | LTC4S | |
| SCHEMBL2755443 | 0.72 | LTC4S (0.66) | LTC4S | |
| SCHEMBL2755461 | 0.71 | LTC4S (1.00) | LTC4S | |
| SCHEMBL3513860 | 0.71 | CYP2C9 (0.67) | CYP1A2CYP2C9PLK1METAP2 | |
| SCHEMBL237373 | 0.70 | LTC4S (0.68) | LTC4S | |
| SCHEMBL239059 | 0.70 | LTC4S (0.69) | LTC4SMETAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120004244-A1 | Bis Aromatic Compounds for Use as LTC4 Synthase Inhibitors | BIOLIPOX AB (SW) | 2012-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004244-A1 | Bis Aromatic Compounds for Use as LTC4 Synthase Inhibitors | LTC4S, LTB4R2, LTB4R | LTC4S 1/4885CYP1A2 64/4885CYP2C9 241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.