Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3269344 | 0.78 | — | — | |
| SCHEMBL12109807 | 0.73 | LMNA (0.38) | ALDH1A1L3MBTL1LMNACYP2A6 | |
| SCHEMBL30191458 | 0.73 | LMNA (0.38) | ALDH1A1L3MBTL1LMNACYP2A6 | |
| SCHEMBL3851901 | 0.70 | LMNA (0.40) | ALDH1A1L3MBTL1LMNA | |
| SCHEMBL31421938 | 0.70 | ERN1 (0.36) | ALDH1A1KDM4EL3MBTL1LMNA | |
| SCHEMBL3272567 | 0.70 | ERN1 (0.44) | ALDH1A1KDM4ELMNACYP2A6 | |
| SCHEMBL3854721 | 0.70 | LMNA (0.38) | ALDH1A1L3MBTL1LMNACYP2A6 | |
| SCHEMBL13076640 | 0.68 | KDM1A (0.35) | ALDH1A1L3MBTL1LMNACYP2A6 | |
| SCHEMBL27339818 | 0.68 | CYP2A6 (0.39) | ALDH1A1LMNACYP2A6 | |
| SCHEMBL12109792 | 0.67 | CYP3A4 (0.34) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1914229-B1 | NOVEL CERCOSPORAMIDE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2010-06-16 | — | — | EP | disclosed |
| US-20090036492-A1 | Novel Cercosporamide Derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2009-02-05 | — | — | US | disclosed |
| CN-101300244-A | Novel cercosporamide derivative | DAIICHI SANKYO CO LTD (JP) | 2008-11-05 | — | — | CN | disclosed |
| EP-1914229-A1 | NOVEL CERCOSPORAMIDE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036492-A1 | Novel Cercosporamide Derivative | GPR119, CBR3, SLC5A2 | ALDH1A1 381/4885KDM4E 3976/4885L3MBTL1 863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.