Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2M | P61081 | 4/20 | 0.41 |
| ▸ | DCUN1D1 | Q96GG9 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25923036 | 1.00 | UBE2M (0.41) | UBE2MDCUN1D1LMNATP53HTT | |
| SCHEMBL25911232 | 0.92 | UBE2M (0.45) | UBE2MDCUN1D1LMNATP53HTT | |
| SCHEMBL30470891 | 0.92 | UBE2M (0.45) | UBE2MDCUN1D1LMNATP53HTT | |
| SCHEMBL24364916 | 0.84 | UBE2M (0.49) | UBE2MDCUN1D1LMNATP53MAPT | |
| SCHEMBL30470618 | 0.84 | UBE2M (0.49) | UBE2MDCUN1D1LMNATP53MAPT | |
| SCHEMBL25321977 | 0.80 | DYRK1A (0.38) | UBE2MDCUN1D1LMNATP53HTT | |
| SCHEMBL25955540 | 0.80 | DYRK1A (0.39) | UBE2MDCUN1D1LMNATP53HTT | |
| SCHEMBL29081611 | 0.80 | SMN1; SMN2 (0.48) | LMNAHTTSMN1; SMN2DYRK1AADORA1 | |
| SCHEMBL30470420 | 0.80 | DYRK1A (0.39) | UBE2MDCUN1D1LMNATP53HTT | |
| SCHEMBL16132861 | 0.79 | NPC1 (0.52) | UBE2MDCUN1D1LMNATP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260078117-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS INC (US) | 2026-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260078117-A1 | COMPOUNDS AND METHODS OF USE | NR3C2, ADRA1A, CNR1 | UBE2M 3818/4885DCUN1D1 2506/4885LMNA 1465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.