SCHEMBL32690403

SCHEMBL32690403

CCc1cc(Nc2ncc(Cl)c(Nc3ccccc3S(=O)(=O)C(F)(F)F)n2)ccc1N1CCOCC1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPK9 P45984 4/20 0.56
▸ MAPK10 P53779 4/20 0.56
▸ MAPK8 P45983 2/20 0.54
▸ CCNK O75909 1/20 0.53
▸ CCNA2 P20248 1/20 0.53
▸ CDK2 P24941 1/20 0.53
▸ CCND3 P30281 1/20 0.53
▸ CDK9 P50750 1/20 0.53
▸ CDK6 Q00534 1/20 0.53
▸ ZAP70 P43403 2/20 0.52
▸ BRD4 O60885 3/20 0.52
▸ MET P08581 1/20 0.52
▸ ALK Q9UM73 1/20 0.52
▸ PTK2 Q05397 3/20 0.51
▸ INSR P06213 1/20 0.51
▸ IGF1R P08069 1/20 0.51
▸ PTK2B Q14289 1/20 0.51
▸ PKMYT1 Q99640 1/20 0.51
▸ AXL P30530 2/20 0.50
▸ SLC2A1 P11166 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32690427 0.87 CCNA2 (0.67) MAPK9MAPK10MAPK8CCNKCCNA2
SCHEMBL31251143 0.77 EGFR (0.60) BRD4ALKAXLNEK2EGFR
SCHEMBL24993662 0.76 MAPK9 (0.48) MAPK9MAPK10MAPK8CCNKCCNA2
SCHEMBL32690365 0.76 ALK (0.60) MAPK9MAPK10MAPK8CCNKCCNA2
SCHEMBL32690420 0.75 PTK2 (0.76) MAPK9MAPK10MAPK8CCNKCCNA2
SCHEMBL12780114 0.75 ZAP70 (0.67) MAPK9MAPK10MAPK8CCNKCCNA2
SCHEMBL29904658 0.73 CDK9 (0.59) MAPK9MAPK10MAPK8CCNKCCNA2
SCHEMBL26906721 0.73 CDK9 (0.59) MAPK9MAPK10MAPK8CCNKCCNA2
SCHEMBL12780515 0.73 ZAP70 (0.82) MAPK9MAPK10MAPK8CCNKCCNA2
SCHEMBL12781687 0.73 ZAP70 (0.64) MAPK9MAPK10MAPK8CCNKCCNA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260085050-A1 TRIPLE KINASE INHIBITORS UNOGEN BIOTECH LTD (US) 2026-03-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260085050-A1 TRIPLE KINASE INHIBITORS ALK, ERBB2, ERBB3 MAPK9 444/4885MAPK10 592/4885MAPK8 348/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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