SCHEMBL32690703

SCHEMBL32690703

O=C(CCc1ccc(S(=O)(=O)Nc2ccc3c(=O)c(O)c(-c4ccccc4C(F)(F)F)[nH]c3c2)cc1)NO

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HDAC1 Q13547 6/20 0.48
▸ HDAC8 Q9BY41 6/20 0.48
▸ HDAC4 P56524 3/20 0.48
▸ BMP1 P13497 1/20 0.38
▸ KMT2A Q03164 2/20 0.38
▸ MEN1 O00255 1/20 0.38
▸ FFAR4 Q5NUL3 3/20 0.36
▸ HDAC6 Q9UBN7 3/20 0.36
▸ HDAC3 O15379 2/20 0.36
▸ HDAC7 Q8WUI4 2/20 0.36
▸ HDAC2 Q92769 2/20 0.36
▸ HDAC10 Q969S8 2/20 0.36
▸ HDAC11 Q96DB2 2/20 0.36
▸ HDAC9 Q9UKV0 2/20 0.36
▸ HDAC5 Q9UQL6 2/20 0.36
▸ FFAR1 O14842 2/20 0.36
▸ RORC P51449 1/20 0.36
▸ MAPT P10636 3/20 0.35
▸ SMN1; SMN2 Q16637 2/20 0.35
▸ ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32690841 0.90 IDO1 (0.41) HDAC1HDAC8HDAC4KMT2AMEN1
SCHEMBL32690754 0.86 FFAR4 (0.48) FFAR4FFAR1SMN1; SMN2ALDH1A1LMNA
SCHEMBL32690778 0.86 HDAC6 (0.42) HDAC1HDAC8HDAC4KMT2AMEN1
SCHEMBL32690793 0.83 HDAC1 (0.48) HDAC1HDAC8HDAC4HDAC6HDAC3
SCHEMBL32690723 0.82 POLB (0.44) KMT2AMEN1FFAR4MAPTSMN1; SMN2
SCHEMBL32690859 0.81 MAP4K4 (0.46) KMT2AMEN1FFAR4FFAR1MAPT
SCHEMBL32690710 0.81 HDAC6 (0.48) HDAC1HDAC8KMT2AMEN1HDAC6
SCHEMBL32690709 0.81 P2RY12 (0.48) HDAC1HDAC8HDAC4HDAC6HDAC3
SCHEMBL32690718 0.80 P2RY12 (0.50) HDAC1HDAC8HDAC4HDAC6HDAC3
SCHEMBL32690717 0.80 P2RY12 (0.50) HDAC1HDAC8HDAC4HDAC6HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260085046-A1 Dual Function Compounds For NADPH Oxidase Inhibition And Histone Deacetylase Inhibition TAIWANJ PHARMACEUTICALS CO LTD (TW) 2026-03-26 — — US claimed
US-20260085046-A1 Dual Function Compounds For NADPH Oxidase Inhibition And Histone Deacetylase Inhibition TAIWANJ PHARMACEUTICALS CO LTD (TW) 2026-03-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260085046-A1 Dual Function Compounds For NADPH Oxidase Inhibition And Histone Deacetylase Inhibition NOX1, NOX4, CYBB HDAC1 7/4885HDAC8 20/4885HDAC4 17/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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