SCHEMBL32690778

SCHEMBL32690778

O=C(NO)c1ccc(S(=O)(=O)Nc2ccc3c(=O)c(O)c(-c4ccccc4C(F)(F)F)[nH]c3c2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HDAC6 Q9UBN7 5/20 0.42
▸ HDAC3 O15379 4/20 0.42
▸ HDAC7 Q8WUI4 2/20 0.42
▸ HDAC10 Q969S8 2/20 0.42
▸ HDAC8 Q9BY41 4/20 0.41
▸ HDAC11 Q96DB2 3/20 0.41
▸ MAPT P10636 3/20 0.41
▸ AVPR2 P30518 2/20 0.40
▸ GPR27 Q9NS67 2/20 0.40
▸ HDAC1 Q13547 3/20 0.39
▸ BRPF1 P55201 1/20 0.39
▸ BRD4 O60885 1/20 0.38
▸ FFAR4 Q5NUL3 3/20 0.38
▸ FFAR1 O14842 1/20 0.38
▸ LMNA P02545 3/20 0.38
▸ ALDH1A1 P00352 1/20 0.38
▸ SMN1; SMN2 Q16637 1/20 0.38
▸ KMT2A Q03164 3/20 0.38
▸ MEN1 O00255 1/20 0.38
▸ NPSR1 Q6W5P4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32690710 0.92 HDAC6 (0.48) HDAC6HDAC3HDAC7HDAC10HDAC8
SCHEMBL32690754 0.90 FFAR4 (0.48) BRD4FFAR4FFAR1LMNAALDH1A1
SCHEMBL32690723 0.89 POLB (0.44) MAPTBRD4FFAR4LMNAALDH1A1
SCHEMBL32690844 0.87 HDAC6 (0.46) HDAC6HDAC3HDAC7HDAC10HDAC8
SCHEMBL32690793 0.87 HDAC1 (0.48) HDAC6HDAC3HDAC7HDAC10HDAC8
SCHEMBL32690703 0.86 HDAC1 (0.48) HDAC6HDAC3HDAC7HDAC10HDAC8
SCHEMBL32690859 0.85 MAP4K4 (0.46) MAPTBRD4FFAR4FFAR1LMNA
SCHEMBL32690856 0.84 HDAC1 (0.40) HDAC6HDAC3HDAC7HDAC10HDAC8
SCHEMBL32690823 0.83 AR (0.49) HDAC6HDAC3HDAC7HDAC10HDAC8
SCHEMBL32690843 0.82 MEN1 (0.46) MAPTLMNAKMT2AMEN1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260085046-A1 Dual Function Compounds For NADPH Oxidase Inhibition And Histone Deacetylase Inhibition TAIWANJ PHARMACEUTICALS CO LTD (TW) 2026-03-26 — — US claimed
US-20260085046-A1 Dual Function Compounds For NADPH Oxidase Inhibition And Histone Deacetylase Inhibition TAIWANJ PHARMACEUTICALS CO LTD (TW) 2026-03-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260085046-A1 Dual Function Compounds For NADPH Oxidase Inhibition And Histone Deacetylase Inhibition NOX1, NOX4, CYBB HDAC6 10/4885HDAC3 9/4885HDAC7 18/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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