SCHEMBL326917

SCHEMBL326917

CC(C)/C=C(\C(N)=O)C(C)C

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 2/20 0.33
GRIA2 P42262 2/20 0.33
GRIA4 P48058 2/20 0.33
GRIK3 Q13003 2/20 0.33
GRIK5 Q16478 2/20 0.33
GRIA1 P42261 1/20 0.33
GRIK2 Q13002 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL157072 1.00 GRIK1 (0.33) GRIK1GRIA2GRIA4GRIK3GRIK5
SCHEMBL26422546 1.00 GRIK1 (0.33) GRIK1GRIA2GRIA4GRIK3GRIK5
Acrylonitrile SCHEMBL28267677 0.84 ALDH1A1 (0.33)
SCHEMBL6703164 0.81 GRIK1 (0.35) GRIK1GRIA2GRIA4GRIK3GRIK5
SCHEMBL6703163 0.81 GRIK1 (0.35) GRIK1GRIA2GRIA4GRIK3GRIK5
SCHEMBL28875766 0.78
SCHEMBL9580637 0.76 GRIK1 (0.39) GRIK1GRIA2GRIA4GRIK3GRIK5
SCHEMBL9580638 0.76 GRIK1 (0.39) GRIK1GRIA2GRIA4GRIK3GRIK5
SCHEMBL10763435 0.76
SCHEMBL18908416 0.76 TSHR (0.32) GRIK1GRIA2GRIA4GRIK3GRIK5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 391 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230055665-A1 DELIVERY CARRIER INTO CELL ITO, KABUSIKIKAISYA (JP) 2023-02-23 US claimed
CN-115135307-A Carrier for cell delivery 株式会社ITO 2022-09-30 CN claimed
CN-107847297-B Dental materials using thermosetting polymers 阿莱恩技术有限公司 2021-10-26 CN claimed
CN-104812790-B Organopolysiloxane graft polymers 花王株式会社 2019-04-12 CN claimed
CN-109097008-A Without native phase high density saturated salt-water drilling fluid fluid loss additive and preparation method thereof 中国石油集团渤海钻探工程有限公司 2018-12-28 CN claimed
CN-108949122-A A kind of heat resisting fluid loss reducing agent and preparation method thereof 中国石油集团工程技术研究院有限公司 2018-12-07 CN claimed
EP-2740153-B1 COOLING DEVICE PROVIDED WITH A THERMOELECTRIC SENSOR COMMISSARIAT ENERGIE ATOMIQUE (FR) 2018-04-04 EP claimed
CN-107847297-A Dental materials using thermosetting polymers 阿莱恩技术有限公司 2018-03-27 CN claimed
US-20180023044-A1 POLYELECTROLYTE COMPLEXES THE CLOROX COMPANY (US) 2018-01-25 US claimed
CN-105295859-B A kind of drilling fluid modified starch fluid loss additive 中国石油化工股份有限公司 2018-01-09 CN claimed
WO-2002044231-A1 SURFACTANT-FREE COSMETIC, DERMATOLOGICAL AND PHARMACEUTICAL AGENTS CLARIANT GMBH (DE) 2002-06-06 WO claimed
EP-0547834-B1 Polymer blends, articles and methods for preparing same MINNESOTA MINING & MFG (US) 1998-05-27 EP claimed
US-5643375-A COEXTRUDING PROPYLENE BASED MATERIAL ALONG WITH NON-CHLORINE CONTAINING POLYMER WHICH IS IMPERMEABLE TO OXYGEN GAS, QUENCHING MULTILAYERED EXTRUDATE, GRAFTING ADDITIONAL LAYER THROUGH EXPOSURE TO DOSAGE OF IONIZING RADIATION MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-07-01 US claimed
US-5407713-A An oxygen impervious ayer of chlorine-free polymer, a moisture impervious layer of a mesophase propylene polymer; radiation resistance, heat sealability, softness; films, pouch, tubes, sealabilty, softness; films, pouch, tubes, tapes and fibers MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-04-18 US claimed
EP-0617665-A1 MULTILAYERED BARRIER STRUCTURES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-10-05 EP claimed
EP-0405793-B1 Radiation resistant heat sealable polymer blends of compatible polymers and methods of preparing same MINNESOTA MINING & MFG (US) 1994-08-03 EP claimed
WO-1993011938-A1 MULTILAYERED BARRIER STRUCTURES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-06-24 WO claimed
EP-0547824-A1 Mesocopolymers, articles, and methods for preparing same MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-06-23 EP claimed
EP-0547834-A1 Polymer blends, articles and methods for preparing same MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-06-23 EP claimed
US-5209984-A Polypropylene, polybutylene, medical packaging, strength MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-05-11 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230055665-A1 DELIVERY CARRIER INTO CELL CTSA, ATG4A, ATG7 GRIK1 3633/4885GRIA2 3522/4885GRIA4 3376/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.