SCHEMBL3269338

SCHEMBL3269338

FC(F)(F)C(Cl)C(F)(F)F

nearest known ligand 0.50

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.50
HSD17B10 Q99714 1/20 0.50
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL407693 1.00 ALDH1A1 (0.50) ALDH1A1HSD17B10MEN1KMT2A
SCHEMBL8157111 0.79 ALDH1A1 (0.41) ALDH1A1HSD17B10MEN1KMT2A
SCHEMBL1990356 0.79 ALDH1A1 (0.41) ALDH1A1HSD17B10MEN1KMT2A
SCHEMBL3845474 0.79 ALDH1A1 (0.41) ALDH1A1HSD17B10MEN1KMT2A
SCHEMBL6903942 0.76 ALDH1A1 (0.39) ALDH1A1HSD17B10MEN1KMT2A
SCHEMBL9066678 0.74 ALDH1A1 (0.54) ALDH1A1HSD17B10MEN1KMT2A
SCHEMBL1479028 0.74
SCHEMBL65852 0.74
SCHEMBL3465262 0.73 ALDH1A1 (0.37) ALDH1A1HSD17B10
SCHEMBL22722069 0.73 ALDH1A1 (0.37) ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2201946-A1 PAI-1 PRODUCTION INHIBITOR Institute of Medicinal Molecular Design, Inc. (JP) 2010-06-30 EP disclosed
US-20090239868-A1 INHIBITOR OF PAI-1 PRODUCTION INSTITUTE OF MEDICAL MOLECULAR DESIGN, INC. 2009-09-24 US disclosed
EP-0248421-B1 Carrier for developer FUJI XEROX CO LTD (JP) 1994-09-07 EP disclosed
US-5110703-A Particles of magnetic powder in binder resin blend of polyolefin and olefin polymer having functional group FUJI XEROX CO., LTD. (JP) 1992-05-05 US disclosed
US-4965160-A CHARGE QUALITY FUJI XEROX CO., LTD. (JP) 1990-10-23 US disclosed
US-4868083-A Developer carrier and process for producing the same FUJI XEROX CO., LTD. (JP) 1989-09-19 US disclosed
US-4791041-A FLUORINATED ALKYL (METH)ARYLATE COPOLYMER OVERCOATINGS; ANTISOILANTS; ANTISTICKING AGENTS FUJI XEROX CO., LTD. (JP) 1988-12-13 US disclosed
EP-0248421-A2 Carrier for developer FUJI XEROX CO., LTD. (JP) 1987-12-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090239868-A1 INHIBITOR OF PAI-1 PRODUCTION SERPINE1, SERPINC1, SERPINH1 ALDH1A1 289/4885HSD17B10 1263/4885MEN1 391/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.