Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 1/20 | 0.53 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3269041 | 0.85 | ESR1 (0.49) | SERPINE1PTGDR2SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL6374160 | 0.82 | KMT2A (0.61) | PTGDR2SMN1; SMN2ALDH1A1HTTHPGD | |
| SCHEMBL10783800 | 0.81 | SERPINE1 (0.62) | SERPINE1SMN1; SMN2ALDH1A1HPGDKMT2A | |
| SCHEMBL3000837 | 0.81 | ESR1 (0.56) | SERPINE1SMN1; SMN2KMT2AMAPTGAA | |
| SCHEMBL1682303 | 0.77 | POLB (0.56) | PTGDR2SMN1; SMN2ALDH1A1HTTHPGD | |
| SCHEMBL28892176 | 0.77 | PTGDR2 (0.46) | SERPINE1PTGDR2SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL14645912 | 0.77 | ESR1 (0.59) | PTGDR2SMN1; SMN2ALDH1A1HTTHPGD | |
| SCHEMBL13778754 | 0.75 | KMT2A (0.58) | SERPINE1PTGDR2SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL5702232 | 0.75 | HPGD (0.65) | PTGDR2SMN1; SMN2ALDH1A1HTTHPGD | |
| SCHEMBL8579998 | 0.74 | ALDH1A1 (0.59) | PTGDR2SMN1; SMN2ALDH1A1HTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110059881-A1 | Sulphur Free Composition And Lubricant Composition And Methods Thereof | THE LUBRIZOL CORPORATION (US) | 2011-03-10 | — | — | US | disclosed |
| EP-1587901-B1 | SULPHUR FREE COMPOSITION AND LUBRICANT COMPOSITION AND METHODS THEREOF | LUBRIZOL CORP (US) | 2010-06-16 | — | — | EP | disclosed |
| US-20060247140-A1 | Sulphur free composition and lubricant composition and methods thereof | LUBRIZOL CORPORATION, THE | 2006-11-02 | — | — | US | disclosed |