Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6374160 | 0.86 | KMT2A (0.61) | POLBMAPTALDH1A1HSD17B10KMT2A | |
| SCHEMBL11253878 | 0.83 | POLB (0.50) | POLBMAPTALDH1A1KDM4EHSD17B10 | |
| SCHEMBL15790266 | 0.83 | KMT2A (0.62) | MAPTALDH1A1KDM4EHSD17B10CYP1A2 | |
| SCHEMBL3269041 | 0.81 | ESR1 (0.49) | MAPTALDH1A1HSD17B10KMT2ANPC1 | |
| SCHEMBL14645912 | 0.80 | ESR1 (0.59) | POLBMAPTALDH1A1CYP1A2KMT2A | |
| SCHEMBL28892176 | 0.80 | PTGDR2 (0.46) | MAPTALDH1A1HSD17B10CYP1A2KMT2A | |
| SCHEMBL25308764 | 0.78 | MAPT (0.62) | POLBMAPTALDH1A1KDM4EHSD17B10 | |
| SCHEMBL3269643 | 0.77 | SERPINE1 (0.53) | POLBMAPTALDH1A1HSD17B10KMT2A | |
| SCHEMBL8009090 | 0.76 | ELANE (0.54) | MAPTALDH1A1HSD17B10CYP1A2KMT2A | |
| SCHEMBL312289 | 0.75 | MAPT (0.67) | POLBMAPTALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003075910-A1 | PREVENTING AND/OR TREATING VASCULAR DISEASE, CARDIOMYOPATHY AND/OR ASSOCIATED HEART FAILURE | PROTEMIX CORPORATION LIMITED (NZ) | 2003-09-18 | — | — | WO | claimed |
| CN-106577678-B | Composition containing succinate dehydrogenase inhibitor | 拱门木材保护有限公司 | 2020-02-07 | — | — | CN | disclosed |
| US-10473662-B2 | Diagnostic and prognostic markers for cancer | WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) | 2019-11-12 | — | — | US | disclosed |
| US-10201161-B2 | Molluscicidal particle, bait and method of controlling harmful molluscs | DE SANGOSSE (FR) | 2019-02-12 | — | — | US | disclosed |
| US-20170082629-A1 | DIAGNOSTIC AND PROGNOSTIC MARKERS FOR CANCER | WAKE FOREST UNIVERSITY HEALTH SCIENCES | 2017-03-23 | — | — | US | disclosed |
| EP-2486154-B1 | DIAGNOSTIC AND PROGNOSTIC MARKERS FOR CANCER | UNIV WAKE FOREST HEALTH SCIENCES (US) | 2017-03-01 | — | — | EP | disclosed |
| US-20170006875-A1 | MOLLUSCICIDAL PARTICLE, BAIT AND METHOD OF CONTROLLING HARMFUL MOLLUSCS | DE SANGOSSE (FR) | 2017-01-12 | — | — | US | disclosed |
| US-20140296098-A1 | Diagnostic and Prognostic Markers for Cancer | UNIV WAKE FOREST HEALTH SCIENCES (US) | 2014-10-02 | — | — | US | disclosed |
| WO-2013023132-A1 | DIAGNOSTIC AND PROGNOSTIC MARKERS FOR CANCER | WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) | 2013-02-14 | — | — | WO | disclosed |
| US-20130012409-A1 | Diagnostic and Prognostic Markers for Cancer | WAKE FOREST UNIVERSITY HEALTH SCIENCES | 2013-01-10 | — | — | US | disclosed |
| US-20120309640-A1 | Diagnostic and Prognostic Markers for Cancer | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-12-06 | — | — | US | disclosed |
| EP-2486154-A1 | DIAGNOSTIC AND PROGNOSTIC MARKERS FOR CANCER | Wake Forest University Health Sciences (US) | 2012-08-15 | — | — | EP | disclosed |
| WO-2011044513-A1 | DIAGNOSTIC AND PROGNOSTIC MARKERS FOR CANCER | WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) | 2011-04-14 | — | — | WO | disclosed |
| WO-2003075910-A1 | PREVENTING AND/OR TREATING VASCULAR DISEASE, CARDIOMYOPATHY AND/OR ASSOCIATED HEART FAILURE | PROTEMIX CORPORATION LIMITED (NZ) | 2003-09-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170006875-A1 | MOLLUSCICIDAL PARTICLE, BAIT AND METHOD OF CONTROLLING HARMFUL MOLLUSCS | SOD1, MDH1, MORF4L1 | POLB 3964/4885MAPT 2408/4885ALDH1A1 269/4885 |
| US-10201161-B2 | Molluscicidal particle, bait and method of controlling harmful molluscs | SOD1, MDH1, MORF4L1 | POLB 3964/4885MAPT 2408/4885ALDH1A1 269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.