Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.48 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.48 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.48 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.47 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.41 |
| ▸ | MERTK | Q12866 | 1/20 | 0.41 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30022211 | 1.00 | GPBAR1 (0.48) | GPBAR1CYSLTR1CYSLTR2TLR7TLR8 | |
| SCHEMBL28608296 | 0.94 | GPBAR1 (0.49) | GPBAR1CYSLTR1CYSLTR2TLR7TLR8 | |
| SCHEMBL13614140 | 0.90 | MAOA (0.46) | GPBAR1CYSLTR1CYSLTR2TLR7HDAC1 | |
| SCHEMBL10614795 | 0.88 | HDAC1 (0.48) | CYSLTR1CYSLTR2HDAC1HDAC2KDM1A | |
| SCHEMBL30388584 | 0.86 | KDM1A (0.50) | CYSLTR1CYSLTR2HDAC1HDAC2KDM1A | |
| SCHEMBL10616742 | 0.84 | KDM1A (0.49) | CYSLTR1CYSLTR2HDAC1HDAC2KDM1A | |
| SCHEMBL1038626 | 0.84 | HDAC1 (0.48) | GPBAR1CYSLTR1CYSLTR2HDAC1HDAC2 | |
| SCHEMBL4725706 | 0.83 | MC4R (0.51) | CYSLTR1CYSLTR2HDAC1HDAC2KDM1A | |
| SCHEMBL1039381 | 0.83 | KDM1A (0.48) | GPBAR1CYSLTR1CYSLTR2HDAC1HDAC2 | |
| SCHEMBL24943587 | 0.82 | HDAC1 (0.55) | CYSLTR1CYSLTR2HDAC1HDAC2KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113307820-B | Quinoline ring-substituted aminophenoxy zinc complex and preparation method and application thereof | 华东理工大学 | 2022-10-25 | — | — | CN | disclosed |
| CN-113307820-A | Quinoline ring-substituted aminophenoxy zinc complex and preparation method and application thereof | 华东理工大学 | 2021-08-27 | — | — | CN | disclosed |
| US-20120004262-A1 | PHENYLCYCLOPROPYLAMINE DERIVATIVES AND THEIR MEDICAL USE | ORYZON GENOMICS, S.A. (ES) | 2012-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004262-A1 | PHENYLCYCLOPROPYLAMINE DERIVATIVES AND THEIR MEDICAL USE | PNMT, ABCB1, SNCA | GPBAR1 317/4885CYSLTR1 2467/4885CYSLTR2 2306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.