SCHEMBL3270586

SCHEMBL3270586

Cc1ccc(C(c2ccc(C)cc2)=[Zr](C2=CC(C(C)(C)C)=CC2C)C2c3cc(C(C)(C)C)ccc3-c3ccc(C(C)(C)C)cc32)cc1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.31
MAPT P10636 1/20 0.31
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16223767 0.91 NPC1 (0.31) NPC1MAPTRAB9A
SCHEMBL15184705 0.90 NPC1 (0.32) NPC1MAPTRAB9A
SCHEMBL2804676 0.90 NPC1 (0.30) NPC1RAB9A
SCHEMBL5071076 0.85
SCHEMBL2803605 0.84
SCHEMBL3268375 0.83 ACHE (0.34)
SCHEMBL5981569 0.81
SCHEMBL3669403 0.81 NPC1 (0.32) NPC1MAPTRAB9A
SCHEMBL2806627 0.81 KCNK9 (0.31) NPC1RAB9A
SCHEMBL15184713 0.81 LMNA (0.31) NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1803742-B1 PROCESS FOR PRODUCING PROPYLENE POLYMER MITSUI CHEMICALS INC (JP) 2010-06-23 EP disclosed
US-20080097055-A1 Process for Producing Propylene Polymer MITSUI CHEMICALS, INC. (JP) 2008-04-24 US disclosed
EP-1803742-A1 PROCESS FOR PRODUCING PROPYLENE POLYMER Mitsui Chemicals, Inc. (JP) 2007-07-04 EP disclosed