Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 5/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TLR2 | O60603 | 2/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | PRKCG | P05129 | 1/20 | 0.33 |
| ▸ | PRKCB | P05771 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | PRKCH | P24723 | 1/20 | 0.33 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.33 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18589803 | 0.85 | LPAR1 (0.39) | LPAR1LPAR3LPAR2USP2SPHK1 | |
| SCHEMBL28837480 | 0.83 | USP2 (0.46) | LPAR1LPAR3LPAR2USP2SPHK1 | |
| SCHEMBL14413744 | 0.83 | LPAR1 (0.38) | LPAR1LPAR3LPAR2USP2SPHK1 | |
| SCHEMBL17145904 | 0.80 | SPHK1 (0.36) | LPAR1LPAR3LPAR2USP2SPHK1 | |
| SCHEMBL16560472 | 0.80 | TSHR (0.44) | LPAR1LPAR3LPAR2USP2SPHK1 | |
| SCHEMBL15151965 | 0.78 | TSHR (0.42) | LPAR1LPAR3LPAR2USP2SPHK1 | |
| SCHEMBL16627345 | 0.78 | USP2 (0.48) | LPAR1LPAR3LPAR2USP2SPHK1 | |
| SCHEMBL16510046 | 0.78 | SPHK1 (0.51) | LPAR1LPAR3LPAR2USP2SPHK1 | |
| SCHEMBL17394527 | 0.78 | LPAR1 (0.37) | LPAR1LPAR3LPAR2USP2SPHK1 | |
| SCHEMBL13314273 | 0.78 | SPHK1 (0.51) | LPAR1LPAR3LPAR2USP2SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120003260-A1 | Solid-Phase and Solution-Phase Synthesis of Glycosylphosphatidylinositol Glycans | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-01-05 | — | — | US | disclosed |
| US-20110256173-A1 | CHEMICAL SYNTHESIS OF PHOSPHATIDYLINOSITOL MANNOSIDE GLYCANS FROM MYCOBACTERIUM TUBERCULOSIS | MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2011-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110256173-A1 | CHEMICAL SYNTHESIS OF PHOSPHATIDYLINOSITOL MANNOSIDE GLYCANS FROM MYCOBACTERIUM TUBERCULOSIS | PIM1, PIM3, PIM2 | LPAR1 4262/4885LPAR3 4098/4885LPAR2 4511/4885 |
| US-20120003260-A1 | Solid-Phase and Solution-Phase Synthesis of Glycosylphosphatidylinositol Glycans | GPI, ALG1, FUT5 | LPAR1 572/4885LPAR3 340/4885LPAR2 503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.