Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 6/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 6/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 5/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 5/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 5/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6003126 | 0.83 | GRIN1 (0.50) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL987369 | 0.83 | GRIN2D (0.31) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL4034994 | 0.79 | MEN1 (0.37) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL20660558 | 0.76 | GRIN2D (0.41) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL3293369 | 0.75 | GRIN2D (0.33) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL5708781 | 0.75 | — | — | |
| SCHEMBL10433767 | 0.70 | GRIN2D (0.31) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL812216 | 0.68 | GRIN1 (0.68) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL1064437 | 0.68 | GRIN2D (0.31) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| Ammonia Solution, Strong SCHEMBL14695768 | 0.66 | GRIN1 (0.65) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 520 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118019736-A | Molecular gel compound designed based on cereblon protein and application thereof | 标新生物医药科技(上海)有限公司 | 2024-05-10 | — | — | CN | claimed |
| EP-4222180-B1 | BIS(HETEROCYCLIC-OLATE) LEWIS BASE CATALYSTS AND METHODS THEREOF | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2024-04-10 | — | — | EP | claimed |
| WO-2024051766-A1 | MOLECULAR GLUE COMPOUND BASED ON CEREBLON PROTEIN DESIGN AND USE THEREOF | 标新生物医药科技(上海)有限公司 | 2024-03-14 | — | — | WO | claimed |
| WO-2024000342-A1 | HYDROPHILICALLY MODIFIED POLYISOCYANATE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 万华化学集团股份有限公司 | 2024-01-04 | — | — | WO | claimed |
| CN-115010902-B | Hydrophilic modified polyisocyanate and preparation method and application thereof | 万华化学集团股份有限公司 | 2023-08-11 | — | — | CN | claimed |
| EP-4222180-A1 | BIS(HETEROCYCLIC-OLATE) LEWIS BASE CATALYSTS AND METHODS THEREOF | ExxonMobil Chemical Patents Inc. (US) | 2023-08-09 | — | — | EP | claimed |
| CN-116323694-A | Bis (heterocyclic-alkoxide) lewis base catalysts and methods thereof | 埃克森美孚化学专利公司 | 2023-06-23 | — | — | CN | claimed |
| CN-111606883-B | Sulfur-containing compound based on glutarimide skeleton and application thereof | 上海科技大学 | 2023-05-09 | — | — | CN | claimed |
| CN-115819720-A | Composite sulfonic acid modified polyisocyanate, preparation method and application thereof | 万华化学集团股份有限公司 | 2023-03-21 | — | — | CN | claimed |
| CN-115010902-A | Hydrophilic modified polyisocyanate and preparation method and application thereof | 万华化学集团股份有限公司 | 2022-09-06 | — | — | CN | claimed |
| EP-1037878-A2 | METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS FOR TREATING CENTRAL NERVOUS SYSTEM DISEASES | NPS PHARMACEUTICALS, INC. (US) | 2000-09-27 | — | — | EP | claimed |
| CN-1056615-C | difluoro pentapeptide derivative anti-inflammatory agents | PROCTER & GAMBLE (US) | 2000-09-20 | — | — | CN | claimed |
| EP-1025079-A1 | $g(a)-ARYL-$i(N)-ALKYLNITRONES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | CENTAUR PHARMACEUTICALS, INC. (US) | 2000-08-09 | — | — | EP | claimed |
| US-6046232-A | THERAPEUTICS FOR TREATING AND/OR PREVENTING NEUROLOGICAL, AUTOIMMUNE AND INFLAMMATORY CONDITIONS IN MAMMALS AND AS ANALYTICAL REAGENTS FOR DETECTING FREE RADICALS | CENTAUR PHARMACEUTICALS, INC. (US) | 2000-04-04 | — | — | US | claimed |
| EP-0904043-B1 | HIGH LATHER STYLING SHAMPOOS | PROCTER & GAMBLE (US) | 2000-02-02 | — | — | EP | claimed |
| EP-0859819-B1 | HEAT-ACTIVATABLE ADHESIVE COMPOSITION | MINNESOTA MINING & MFG (US) | 1999-12-29 | — | — | EP | claimed |
| WO-1999026927-A2 | METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS FOR TREATING CENTRAL NERVOUS SYSTEM DISEASES | NPS PHARMACEUTICALS, INC. (US) | 1999-06-03 | — | — | WO | claimed |
| WO-1999020601-A1 | α-ARYL-N-ALKYLNITRONES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | CENTAUR PHARMACEUTICALS, INC. (US) | 1999-04-29 | — | — | WO | claimed |
| CN-1095072-A | Difluoro pentapeptide derivative anti-inflammatory agents | PROCTER & GAMBLE (US) | 1994-11-16 | — | — | CN | claimed |
| EP-0154339-B1 | OPTICAL FIBER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-06-07 | — | — | EP | claimed |