Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 3/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL327129 | 0.75 | GRIN1 (0.41) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL2395911 | 0.74 | GRIN2D (0.31) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL25216482 | 0.71 | GRIN2D (0.58) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL5670500 | 0.70 | — | — | |
| SCHEMBL4436229 | 0.70 | — | — | |
| SCHEMBL11246246 | 0.70 | — | — | |
| SCHEMBL3512411 | 0.70 | GRIN2D (0.50) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL216451 | 0.70 | PKM (0.37) | — | |
| SCHEMBL27829376 | 0.70 | GRIN2D (0.33) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL4344337 | 0.70 | GRIN2D (0.44) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 338 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008009680-A1 | NOVEL HYDROGEN-RICH 1,3-DIALKOXYDISILOXANES AND PROCESSES FOR THEIR PREPARATION AND THEIR USE | TECHNISCHE UNIVERSITÄT BERGAKADEMIE FREIBERG (DE) | 2008-01-24 | — | — | WO | claimed |
| EP-0343961-B1 | Aryl- and heteroaryl piperazinyl carboxamides having central nervous system activity | AMERICAN HOME PROD (US) | 1996-01-10 | — | — | EP | claimed |
| US-5482940-A | OBESITY, ALCOHOLISM | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-01-09 | — | — | US | claimed |
| US-5391571-A | Cholesterol ester hydrolase inhibitors | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-02-21 | — | — | US | claimed |
| US-5380725-A | Antipsychotic agents and anxiolytic agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-01-10 | — | — | US | claimed |
| US-5278160-A | Treating aggressive behavior | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-01-11 | — | — | US | claimed |
| US-5254552-A | Cognition activators, psychological disorders | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-10-19 | — | — | US | claimed |
| US-5106849-A | Treating anxiety, depression, psychoses | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-04-21 | — | — | US | claimed |
| EP-0428385-A1 | Cholesterol ester hydrolase inhibitors | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-05-22 | — | — | EP | claimed |
| US-5010078-A | Anxiolytic, antidepressant agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-04-23 | — | — | US | claimed |
| EP-0343961-A2 | Aryl- and heteroaryl piperazinyl carboxamides having central nervous system activity | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-11-29 | — | — | EP | claimed |
| US-4797489-A | ANTIDEPRESSANTS, ANXIOLYTIC AGENTS | AMERICAN HOME PRODUCTS CORP. (US) | 1989-01-10 | — | — | US | claimed |
| EP-4400317-A1 | INKJET INK, INK SET, IMAGE-RECORDING METHOD, AND PRODUCTION METHOD FOR LAMINATE BODY | FUJIFILM Corporation (JP) | 2024-07-17 | — | — | EP | disclosed |
| US-20240231226-A1 | SALT, ACID GENERATOR, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2024-07-11 | — | — | US | disclosed |
| US-20240219830-A1 | SALT, ACID GENERATOR, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2024-07-04 | — | — | US | disclosed |
| US-20240210823-A1 | CARBOXYLATE, CARBOXYLIC ACID GENERATOR, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2024-06-27 | — | — | US | disclosed |
| EP-0343961-A2 | Aryl- and heteroaryl piperazinyl carboxamides having central nervous system activity | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-11-29 | — | — | EP | disclosed |
| US-4835177-A | Aminoalkyl naphthalenediols as host resistance enhancers against viral infection | MERCK & CO., INC. (US) | 1989-05-30 | — | — | US | disclosed |
| US-4797489-A | ANTIDEPRESSANTS, ANXIOLYTIC AGENTS | AMERICAN HOME PRODUCTS CORP. (US) | 1989-01-10 | — | — | US | disclosed |
| US-4797489-A | ANTIDEPRESSANTS, ANXIOLYTIC AGENTS | AMERICAN HOME PRODUCTS CORP. (US) | 1989-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240219830-A1 | SALT, ACID GENERATOR, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN | H1-0, HCN3, RER1 | GRIN2D 266/4885GRIN3B 552/4885GRIN1 169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.