Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 4/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.50 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.50 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.50 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL327129 | 0.83 | GRIN1 (0.41) | GRIN1GRIN2ALMNAGRIN2DGRIN3B | |
| SCHEMBL987369 | 0.73 | GRIN2D (0.31) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL4340088 | 0.70 | MEN1 (0.38) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL4034994 | 0.69 | MEN1 (0.37) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL6229112 | 0.68 | MEN1 (0.37) | HTT | |
| Memantine SCHEMBL23327176 | 0.68 | GRIN1 (1.00) | GRIN1GRIN2ALMNAGRIN2DGRIN3B | |
| Memantine SCHEMBL8126868 | 0.68 | GRIN1 (1.00) | GRIN1GRIN2ALMNAGRIN2DGRIN3B | |
| Memantine SCHEMBL13198606 | 0.68 | GRIN1 (1.00) | GRIN1GRIN2ALMNAGRIN2DGRIN3B | |
| SCHEMBL5608589 | 0.68 | GRIN1 (0.90) | GRIN1GRIN2ALMNAGRIN2DGRIN3B | |
| Memantine SCHEMBL2688 | 0.68 | GRIN1 (1.00) | GRIN1GRIN2ALMNAGRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060199816-A1 | Aryl sulfonyl piperidines | GILLESPIE PAUL | 2006-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060199816-A1 | Aryl sulfonyl piperidines | GPR119, SLC5A2, GLS2 | GRIN1 3356/4885GRIN2A 2397/4885LMNA 3687/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.