SCHEMBL3271304

SCHEMBL3271304

CCCCC1Cc2ccccc2C1(C)C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.37
MEN1 O00255 1/20 0.37
CYP2D6 P10635 1/20 0.37
ALOX15 P16050 1/20 0.37
CYP2C19 P33261 1/20 0.37
KMT2A Q03164 1/20 0.37
GRIN2D O15399 1/20 0.37
GRIN3B O60391 1/20 0.37
BCHE P06276 1/20 0.37
CHRM5 P08912 1/20 0.37
TSHR P16473 1/20 0.37
ALOX12 P18054 1/20 0.37
NFKB1 P19838 1/20 0.37
MAPK1 P28482 1/20 0.37
PRCP P42785 1/20 0.37
GRIN1 Q05586 1/20 0.37
GRIN2A Q12879 1/20 0.37
GRIN2B Q13224 1/20 0.37
GRIN2C Q14957 1/20 0.37
GRIN3A Q8TCU5 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7790087 0.81 SIGMAR1 (0.35) ALOX12
SCHEMBL7790061 0.76 SIGMAR1 (0.35)
SCHEMBL7782467 0.75 SIGMAR1 (0.37) CYP2D6CYP2C19
SCHEMBL7788013 0.75 SIGMAR1 (0.37) CYP2D6CYP2C19
SCHEMBL7790327 0.75 SIGMAR1 (0.37) CYP2D6CYP2C19
SCHEMBL20561510 0.75 CYP3A4 (0.38) CYP3A4MEN1CYP2D6ALOX15CYP2C19
SCHEMBL11207439 0.72 CYSLTR2 (0.35)
SCHEMBL7258924 0.71
SCHEMBL9642300 0.71 DRD2 (0.37) CYP3A4TSHRMAPK1
SCHEMBL29649120 0.71 DRD2 (0.37) CYP3A4TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103012044-A Preparation method of 6-tert-butyl-1,1-dimethyldihydroindene UNIV ZHEJIANG 2013-04-03 CN claimed
CN-1205199-C Perfume parent GIVAUDAN SA (CH) 2005-06-08 CN claimed
CN-1330070-A Perfume parent GIVAUDAN SA (CH) 2002-01-09 CN claimed
CN-1317475-A Perfumery precursor GIVAUDAN SA (CH) 2001-10-17 CN claimed
CN-109642184-A Product including plastic containers and composition of matter 西姆莱斯有限公司 2019-04-16 CN disclosed
CN-108473484-A Compounds useful as TRPM8 modulators 赛诺米克斯公司 2018-08-31 CN disclosed
CN-108367088-A Composition and the conveyer system for spraying two or more compositions and filler 约翰逊父子公司 2018-08-03 CN disclosed
CN-103249826-B Fragrance granules for detergents SYMRISE AG 2015-07-15 CN disclosed
CN-104769092-A Fabric care compositions comprising emulsions DOW CORNING 2015-07-08 CN disclosed
CN-104395377-A Aqueous silicone dispersions and films and their preparation DOW CORNING 2015-03-04 CN disclosed
CN-103012044-A Preparation method of 6-tert-butyl-1,1-dimethyldihydroindene UNIV ZHEJIANG 2013-04-03 CN disclosed
CN-102174252-B Non-textile polymer compositions and methods INVISTA TECH SARL 2013-03-27 CN disclosed
CN-1225122-A Detergent composition PROCTER & GAMBLE (US) 1999-08-04 CN disclosed
CN-1222186-A Mid-chain branched primary alkyl alkoxylated sulfate surfactants PROCTER & GAMBLE (US) 1999-07-07 CN disclosed
CN-1222184-A Detergent compsns. containing selected mid-chain branched surfactants PROCTER & GAMBLE (US) 1999-07-07 CN disclosed
CN-1222188-A Mid-chain branched primary alkyl sulfates as surfactants PROCTER & GAMBLE (US) 1999-07-07 CN disclosed
EP-0905118-A1 Unsaturated 6-tert-butyl-1,1-dimethylindane derivates substituted in the 4-position and their use in human and veterinary medicine as well as in cosmetics Galderma Research & Development, S.N.C. (FR) 1999-03-31 EP disclosed
CN-1185804-A Bleaching compositions comprising selective perfumes for masking bleach odor PROCTER & GAMBLE (US) 1998-06-24 CN disclosed
US-5156766-A Nonionic emulsifiers, liquid hydrophobic system, perfumy stabilizer and other surfactants UNILEVER PATENT HOLDINGS, B.V. (NL) 1992-10-20 US disclosed
US-4439353-A ORGANOLEPTIC GIVAUDAN CORPORATION (US) 1984-03-27 US disclosed