SCHEMBL327149

SCHEMBL327149

CCCCCn1cnc2ccccc21

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.70
SMN1; SMN2 Q16637 7/20 0.65
LMNA P02545 6/20 0.65
TSHR P16473 2/20 0.65
ALOX15 P16050 1/20 0.65
HTT P42858 5/20 0.62
MAPT P10636 3/20 0.62
STAT3 P40763 1/20 0.62
MEN1 O00255 2/20 0.61
KMT2A Q03164 2/20 0.61
NPC1 O15118 1/20 0.56
NFKB1 P19838 1/20 0.56
RAB9A P51151 1/20 0.56
NFKB2 Q00653 1/20 0.56
RELA Q04206 1/20 0.56
EGLN3 Q9H6Z9 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
DRD2 P14416 1/20 0.54
DRD4 P21917 1/20 0.54
DRD3 P35462 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11408718 0.98 TDP1 (0.68) TDP1SMN1; SMN2LMNATSHRALOX15
SCHEMBL595111 0.98 TDP1 (0.68) TDP1SMN1; SMN2LMNATSHRALOX15
SCHEMBL16097150 0.98 TDP1 (0.68) TDP1SMN1; SMN2LMNATSHRALOX15
SCHEMBL3868979 0.98 TDP1 (0.68) TDP1SMN1; SMN2LMNATSHRALOX15
SCHEMBL4888041 0.98 TDP1 (0.68) TDP1SMN1; SMN2LMNATSHRALOX15
SCHEMBL9038701 0.98 TDP1 (0.68) TDP1SMN1; SMN2LMNATSHRALOX15
SCHEMBL6321085 0.98 TDP1 (0.68) TDP1SMN1; SMN2LMNATSHRALOX15
SCHEMBL9853336 0.98 TDP1 (0.68) TDP1SMN1; SMN2LMNATSHRALOX15
SCHEMBL9038339 0.98 TDP1 (0.68) TDP1SMN1; SMN2LMNATSHRALOX15
SCHEMBL9853294 0.98 TDP1 (0.68) TDP1SMN1; SMN2LMNATSHRALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 537 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240074218-A1 ORGANIC PHOTOSENSITIVE DEVICES WITH EXCITON-BLOCKING CHARGE CARRIER FILTERS U.S. DEPARTMENT OF ENERGY 2024-02-29 US claimed
CN-117263869-A Method for synthesizing N-aryl benzimidazole derivative 郑州轻工业大学 2023-12-22 CN claimed
US-20200062782-A1 BIFUNCTIONAL ALPHA-SYNUCLEIN BINDING AGENTS AND USES THEREOF UNIVERSITY OF SASKATCHEWAN (CA) 2020-02-27 US claimed
CN-110819445-A Method for removing polycyclic aromatic hydrocarbon from grease 丰益(上海)生物技术研发中心有限公司 2020-02-21 CN claimed
EP-2984690-B1 ORGANIC PHOTOSENSITIVE DEVICES WITH EXCITON-BLOCKING CHARGE CARRIER FILTERS UNIV MICHIGAN REGENTS (US) 2020-02-19 EP claimed
US-10269870-B2 Organic light-emitting device, production method thereof, and display apparatus BOE TECHNOLOGY GROUP CO., LTD. (CN) 2019-04-23 US claimed
CN-105556693-B Organic photosensitive device with exciton blocking charge carrier filter 密歇根大学董事会 2018-09-21 CN claimed
US-10069095-B2 Organic photosensitive devices with exciton-blocking charge carrier filters UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2018-09-04 US claimed
WO-2018148224-A1 PHOSPHOLIPID ETHER (PLE) CAR T CELL TUMOR TARGETING (CTCT) AGENTS Seattle Children's Hospital (dba Seattle Children's Research Institute) (US) 2018-08-16 WO claimed
US-20180204887-A1 ORGANIC LIGHT-EMITTING DEVICE, PRODUCTION METHOD THEREOF, AND DISPLAY APPARATUS BOE TECHNOLOGY GROUP CO., LTD. (CN) 2018-07-19 US claimed
EP-1404696-B1 ACTIVATORS FOR OLIGONUCLEOTIDE SYNTHESIS AVECIA BIOTECHNOLOGY INC (US) 2006-02-08 EP claimed
CN-1700831-A Full-wavelength white-light organic electroluminescent device and manufacturing method thereof WINTEK CORP (CN) 2005-11-23 CN claimed
US-20050164033-A1 White light emitting organic electroluminescent device and organic electroluminescent display having the same SAMSUNG DISPLAY CO., LTD. (KR) 2005-07-28 US claimed
US-20040185298-A1 Red-emitting organic electroluminescent elements CITY UNIVERSITY OF HONG KONG (CN) 2004-09-23 US claimed
EP-1404696-A1 ACTIVATORS FOR OLIGONUCLEOTIDE SYNTHESIS Avecia Biotechnology, Inc. (US) 2004-04-07 EP claimed
WO-2003004512-A1 ACTIVATORS FOR OLIGONUCLEOTIDE SYNTHESIS AVECIA BIOTECHNOLOGY INC. (US) 2003-01-16 WO claimed
EP-0794847-B1 PROCESS FOR BONDING WIRES TO OXIDATION-SENSITIVE METAL SUBSTRATES WHICH CAN BE SOLDERED ATOTECH DEUTSCHLAND GMBH (DE) 1998-07-22 EP claimed
EP-0555460-B1 FILTERING COSMETIC COMPOSITION COMPRISING A NANOPIGMENT OF METAL OXIDE AND A LIPOSOLUBLE FILTER POLYMER OREAL (FR) 1995-05-31 EP claimed
EP-0555460-A1 FILTERING COSMETIC COMPOSITION COMPRISING A NANOPIGMENT OF METAL OXIDE AND A LIPOSOLUBLE FILTER POLYMER. OREAL (FR) 1993-08-18 EP claimed
WO-1993004666-A1 FILTERING COSMETIC COMPOSITION COMPRISING A NANOPIGMENT OF METAL OXIDE AND A LIPOSOLUBLE FILTER POLYMER L'OREAL (FR) 1993-03-18 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200062782-A1 BIFUNCTIONAL ALPHA-SYNUCLEIN BINDING AGENTS AND USES THEREOF SNCA, PARK7, SYNJ2 TDP1 222/4885SMN1; SMN2 31/4885LMNA 2756/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.