SCHEMBL3271637

SCHEMBL3271637

CC1(C)CCCC2(C1)CC2(C)C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.37
POLB P06746 1/20 0.31
LMNA P02545 1/20 0.31
TSHR P16473 1/20 0.31
NFKB1 P19838 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3272005 0.82 FFAR3 (0.40) FFAR3POLBLMNATSHRCYP2C19
SCHEMBL6265218 0.82 FFAR3 (0.40) FFAR3POLBLMNATSHRCYP2C19
Bicarbonate SCHEMBL10668252 0.76 FFAR3 (0.41) FFAR3LMNATSHRNFKB1CYP2C19
SCHEMBL19433865 0.75 FFAR3 (0.42) FFAR3POLBLMNATSHRNFKB1
Acetic Acid SCHEMBL4356996 0.74 FFAR3 (0.39) FFAR3TSHRNFKB1CYP2C19
SCHEMBL3271811 0.74 SMN1; SMN2 (0.38) POLBLMNA
SCHEMBL29184377 0.73 FFAR3 (0.50) FFAR3POLBLMNATSHRNFKB1
SCHEMBL5804349 0.73 FFAR3 (0.52) FFAR3TSHRNFKB1CYP2C19
SCHEMBL30148860 0.72 ALDH1A1 (0.33) FFAR3POLBLMNA
Ammonia Solution, Strong SCHEMBL27985130 0.71 FFAR3 (0.50) FFAR3TSHRNFKB1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7687452-B2 2-(3,3-dimethylcyclohexyl)propionic acid ethoxycarbonylmethyl ester; 1,5,5-trimethylspiro[2.5]octane-1-carboxylic acid ethoxycarbonylmethyl ester; new powerful musk odorants GIVAUDAN SA (CH) 2010-03-30 US disclosed
EP-1743013-B1 ALICYCLIC CARBOXYLIC ACID OXYCARBONYLMETHYL ESTERS AND THEIR USE AS ODORANTS GIVAUDAN SA (CH) 2007-12-19 EP disclosed
US-20070225201-A1 Organic Compounds GIVAUDAN SA (CH) 2007-09-27 US disclosed