Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | APLNR | P35414 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL27985130 | 0.98 | FFAR3 (0.50) | FFAR3TSHRNFKB1CYP2C19APLNR | |
| SCHEMBL14514521 | 0.93 | FFAR3 (0.50) | FFAR3CYP2C19APLNRALDH1A1SMN1; SMN2 | |
| SCHEMBL14137689 | 0.89 | FFAR3 (0.58) | FFAR3CYP2C19ALDH1A1SMN1; SMN2 | |
| SCHEMBL17893172 | 0.87 | FFAR3 (0.60) | FFAR3TSHRNFKB1CYP2C19ALDH1A1 | |
| SCHEMBL264769 | 0.82 | — | — | |
| SCHEMBL11292104 | 0.81 | FFAR3 (0.67) | FFAR3TSHRNFKB1CYP2C19APLNR | |
| Bicarbonate SCHEMBL10668252 | 0.79 | FFAR3 (0.41) | FFAR3TSHRNFKB1CYP2C19APLNR | |
| Hydrochloric Acid SCHEMBL11826255 | 0.79 | — | — | |
| SCHEMBL17771548 | 0.79 | FFAR3 (0.50) | FFAR3TSHRNFKB1CYP2C19 | |
| SCHEMBL25886393 | 0.78 | FFAR3 (0.40) | FFAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060276505-A1 | Acylhydrazine P2X7 antagonists and uses thereof | ABBOTT LABORATORIES | 2006-12-07 | — | — | US | disclosed |
| WO-2006110516-A1 | ACYLHYDRAZIDE P2X7 ANTAGONISTS AND USES THEREOF | ABBOTT LABORATORIES (US) | 2006-10-19 | — | — | WO | disclosed |
| US-4249015-A | Preparation of organic acids and/or esters | SHELL OIL COMPANY (US) | 1981-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276505-A1 | Acylhydrazine P2X7 antagonists and uses thereof | P2RX7, P2RX3, P2RX1 | FFAR3 82/4885TSHR 895/4885NFKB1 2241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.