Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 11/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.35 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.35 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.35 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.35 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.35 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.35 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.35 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9378856 | 0.83 | LOXL2 (0.40) | LOXL2MAOAGLASTING1ACHE | |
| SCHEMBL3268239 | 0.80 | GLA (0.58) | LOXL2MAOAGLASTING1MEN1 | |
| Acetic Acid SCHEMBL3273667 | 0.78 | GLA (0.44) | MAOAGLASTING1ACHEMAOB | |
| SCHEMBL15678569 | 0.77 | LOXL2 (0.50) | LOXL2MAOAGLASTING1EGFR | |
| SCHEMBL3271029 | 0.76 | STING1 (0.71) | MAOAGLASTING1MEN1KMT2A | |
| SCHEMBL13395985 | 0.76 | GLA (0.57) | MAOAGLASTING1ACHEMAOB | |
| SCHEMBL3267207 | 0.72 | GLA (0.53) | MAOAGLASTING1MEN1KMT2A | |
| SCHEMBL16177041 | 0.70 | MAOB (0.45) | LOXL2MAOAMAOBESR2 | |
| SCHEMBL12093432 | 0.69 | LOXL2 (0.47) | LOXL2MAOAMAOBMEN1KMT2A | |
| SCHEMBL29450783 | 0.69 | LOXL2 (0.47) | LOXL2MAOAMAOBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8350065-B2 | 5,6-dimethyl xanthone-4-acetic acid derivatives and method of preparing the same | GRAND PHARMA (CHINA) CO., LTD. (CN) | 2013-01-08 | — | — | US | disclosed |
| US-8350065-B2 | 5,6-dimethyl xanthone-4-acetic acid derivatives and method of preparing the same | GRAND PHARMA (CHINA) CO., LTD. (CN) | 2013-01-08 | — | — | US | disclosed |
| US-8350065-B2 | 5,6-dimethyl xanthone-4-acetic acid derivatives and method of preparing the same | GRAND PHARMA (CHINA) CO., LTD. (CN) | 2013-01-08 | — | — | US | disclosed |
| EP-2196463-A1 | PREPARATION OF 5,6-DIMETHYLXANTHONE-4-ACETIC ACID, THE DERIVATIVES PREPARED AND PHARMACEUTICAL FORMULATIONS THEREOF | Wuhan Grand Pharmaceutical Group Co., Ltd (CN) | 2010-06-16 | — | — | EP | disclosed |
| EP-2196463-A1 | PREPARATION OF 5,6-DIMETHYLXANTHONE-4-ACETIC ACID, THE DERIVATIVES PREPARED AND PHARMACEUTICAL FORMULATIONS THEREOF | Wuhan Grand Pharmaceutical Group Co., Ltd (CN) | 2010-06-16 | — | — | EP | disclosed |
| US-20100099754-A1 | 5,6-DIMETHYL XANTHONE-4-ACETIC ACID DERIVATIVES AND METHOD OF PREPARING THE SAME | GRAND PHARMA (CHINA) CO., LTD. (CN) | 2010-04-22 | — | — | US | disclosed |
| US-20100099754-A1 | 5,6-DIMETHYL XANTHONE-4-ACETIC ACID DERIVATIVES AND METHOD OF PREPARING THE SAME | GRAND PHARMA (CHINA) CO., LTD. (CN) | 2010-04-22 | — | — | US | disclosed |
| US-20100099754-A1 | 5,6-DIMETHYL XANTHONE-4-ACETIC ACID DERIVATIVES AND METHOD OF PREPARING THE SAME | GRAND PHARMA (CHINA) CO., LTD. (CN) | 2010-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099754-A1 | 5,6-DIMETHYL XANTHONE-4-ACETIC ACID DERIVATIVES AND METHOD OF PREPARING THE SAME | HCAR2, HAO2, HK2 | LOXL2 1152/4885MAOA 131/4885GLA 2459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.