Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1311847 | 0.83 | CYP3A4 (0.38) | CYP1A2ERN1CYP3A4MAPTALDH1A1 | |
| SCHEMBL19825897 | 0.82 | ERN1 (0.35) | CYP1A2ERN1CYP3A4MAPTPRKDC | |
| SCHEMBL25637321 | 0.78 | ERN1 (0.33) | ERN1CYP3A4MAPTPRKDC | |
| SCHEMBL3272274 | 0.77 | PRKDC (0.36) | CYP1A2ERN1CYP3A4MAPTPRKDC | |
| SCHEMBL14703277 | 0.75 | ERN1 (0.33) | ERN1PRKDC | |
| SCHEMBL1313257 | 0.73 | CYP3A4 (0.35) | CYP1A2ERN1CYP3A4MAPTALDH1A1 | |
| SCHEMBL12689899 | 0.73 | PRKDC (0.36) | CYP1A2ERN1CYP3A4MAPTPRKDC | |
| SCHEMBL16684728 | 0.72 | CYP3A4 (0.49) | ERN1CYP3A4MAPTALDH1A1 | |
| SCHEMBL31459749 | 0.72 | CYP1A2 (0.36) | CYP1A2ERN1CYP3A4MAPT | |
| SCHEMBL21378953 | 0.72 | ERN1 (0.33) | ERN1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1914229-B1 | NOVEL CERCOSPORAMIDE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2010-06-16 | — | — | EP | disclosed |
| US-20090036492-A1 | Novel Cercosporamide Derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2009-02-05 | — | — | US | disclosed |
| EP-1914229-A1 | NOVEL CERCOSPORAMIDE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036492-A1 | Novel Cercosporamide Derivative | GPR119, CBR3, SLC5A2 | CYP1A2 972/4885ERN1 337/4885CYP3A4 1027/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.