Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | ACP1 | P24666 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1311847 | 0.83 | CYP3A4 (0.38) | ERN1LMNATSHRCYP3A4MAPT | |
| SCHEMBL12689899 | 0.82 | PRKDC (0.36) | PRKDCERN1LMNATSHRCYP3A4 | |
| SCHEMBL8459050 | 0.81 | ERN1 (0.43) | ERN1LMNACYP3A4MAPTCYP1A2 | |
| SCHEMBL27303408 | 0.78 | PRKDC (0.43) | PRKDCERN1LMNATSHRMAPT | |
| SCHEMBL3271920 | 0.77 | CYP1A2 (0.35) | PRKDCERN1LMNACYP3A4MAPT | |
| SCHEMBL29266716 | 0.77 | CA1 (0.33) | PRKDCERN1LMNATSHRCYP3A4 | |
| SCHEMBL7700297 | 0.74 | ALDH1A1 (0.39) | PRKDCERN1LMNATSHRCYP3A4 | |
| SCHEMBL15370277 | 0.73 | SRC (0.41) | PRKDCCYP1A2 | |
| SCHEMBL18300001 | 0.73 | ERN1 (0.40) | PRKDCERN1TSHR | |
| SCHEMBL11993044 | 0.73 | ERN1 (0.44) | PRKDCERN1LMNATSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1914229-B1 | NOVEL CERCOSPORAMIDE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2010-06-16 | — | — | EP | disclosed |
| US-20090036492-A1 | Novel Cercosporamide Derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2009-02-05 | — | — | US | disclosed |
| EP-1914229-A1 | NOVEL CERCOSPORAMIDE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036492-A1 | Novel Cercosporamide Derivative | GPR119, CBR3, SLC5A2 | PRKDC 2531/4885ERN1 337/4885LMNA 4110/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.