Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.43 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3655574 | 0.79 | SMN1; SMN2 (0.59) | KDM4ENLRP3CXCL8L3MBTL1LMNA | |
| SCHEMBL8654103 | 0.77 | ALDH1A1 (0.58) | KDM4EHSD17B10SOAT1L3MBTL1NPC1 | |
| SCHEMBL28593578 | 0.76 | CXCL8 (0.52) | POLBNLRP3CXCL8RAB9ASMN1; SMN2 | |
| SCHEMBL11467737 | 0.75 | CXCL8 (0.49) | CXCL8L3MBTL1 | |
| SCHEMBL1165782 | 0.73 | CYSLTR2 (0.59) | L3MBTL1LMNAMAPTTSHR | |
| SCHEMBL17183962 | 0.73 | ALDH1A1 (0.60) | KDM4EHSD17B10SOAT1L3MBTL1NPC1 | |
| SCHEMBL4041854 | 0.72 | CYSLTR2 (0.61) | L3MBTL1LMNAMAPT | |
| SCHEMBL4127567 | 0.72 | POLB (0.53) | POLBL3MBTL1LMNANPC1MAPT | |
| SCHEMBL4127562 | 0.72 | POLB (0.53) | POLBL3MBTL1LMNANPC1MAPT | |
| SCHEMBL6121220 | 0.71 | CXCL8 (0.54) | NLRP3CXCL8HSD17B10L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590931-A1 | (2-ARYLOXY-ACETYLAMINO)-PHENYL-PROPIONIC ACID DERIVATIVES, METHOD FOR PRODUCING SAME AND USE THEREOF AS PHARMACEUTICALS | SANOFI (FR) | 2013-05-15 | — | — | EP | disclosed |
| CN-103080073-A | (2-Aryloxyacetylamino) phenyl-propionic acid derivatives, method for the production thereof and use thereof as medicaments | SANOFI SA | 2013-05-01 | — | — | CN | disclosed |
| WO-2012004269-A1 | (2-ARYLOXY-ACETYLAMINO)-PHENYL-PROPIONIC ACID DERIVATIVES, METHOD FOR PRODUCING SAME AND USE THEREOF AS PHARMACEUTICALS | SANOFI (FR) | 2012-01-12 | — | — | WO | disclosed |