Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | ERN1 | O75460 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1666901 | 0.91 | PADI4 (0.48) | PADI4ALDH1A1ERN1LMNAMAPT | |
| SCHEMBL30229866 | 0.88 | PADI4 (0.45) | PADI4ALDH1A1ERN1LMNAMAPT | |
| SCHEMBL9838922 | 0.88 | PADI4 (0.45) | PADI4ALDH1A1ERN1LMNAMAPT | |
| SCHEMBL4164444 | 0.86 | PADI4 (0.52) | PADI4ALDH1A1ERN1LMNAMAPT | |
| SCHEMBL29802335 | 0.86 | PADI4 (0.52) | PADI4ALDH1A1ERN1LMNAMAPT | |
| SCHEMBL4776430 | 0.81 | PADI4 (0.44) | PADI4ALDH1A1ERN1LMNAMAPT | |
| SCHEMBL3268833 | 0.81 | PADI4 (0.64) | PADI4ALDH1A1ERN1LMNAHTT | |
| SCHEMBL5248091 | 0.79 | CYP1A2 (0.36) | PADI4ALDH1A1MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL7192168 | 0.79 | CYP1A2 (0.36) | PADI4ALDH1A1NPSR1L3MBTL1CYP1A2 | |
| SCHEMBL986883 | 0.77 | PADI4 (0.64) | PADI4ALDH1A1ERN1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101310716-A | Therapeutic agent | TAKARA BIO INC (JP) | 2008-11-26 | — | — | CN | claimed |
| CN-1791392-A | Therapeutic agents | TAKARA BIO INC (JP) | 2006-06-21 | — | — | CN | claimed |
| EP-1914229-B1 | NOVEL CERCOSPORAMIDE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2010-06-16 | — | — | EP | disclosed |
| US-20090036492-A1 | Novel Cercosporamide Derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2009-02-05 | — | — | US | disclosed |
| CN-101310716-A | Therapeutic agent | TAKARA BIO INC (JP) | 2008-11-26 | — | — | CN | disclosed |
| CN-100415218-C | Therapeutic agents | TAKARA BIO INC (JP) | 2008-09-03 | — | — | CN | disclosed |
| EP-1914229-A1 | NOVEL CERCOSPORAMIDE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| CN-1791392-A | Therapeutic agents | TAKARA BIO INC (JP) | 2006-06-21 | — | — | CN | disclosed |
| EP-0124992-B1 | HERBICIDAL CYCLOHEXANE-1,3-DIONE DERIVATIVES | ICI AUSTRALIA LIMITED (AU) | 1991-05-29 | — | — | EP | disclosed |
| US-4680400-A | Herbicidal cyclohexane-1,3-dione-5-isoquinoline derivatives | ICI AUSTRALIA LIMITED (AU) | 1987-07-14 | — | — | US | disclosed |
| US-4640708-A | Herbicidal cyclohexane-1,3-dione derivatives | ICI AUSTRALIA LIMITED (AU) | 1987-02-03 | — | — | US | disclosed |
| EP-0124992-A1 | Herbicidal cyclohexane-1,3-dione derivatives | ICI AUSTRALIA LIMITED (AU) | 1984-11-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036492-A1 | Novel Cercosporamide Derivative | GPR119, CBR3, SLC5A2 | PADI4 3251/4885ALDH1A1 381/4885ERN1 337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.