SCHEMBL7192168

SCHEMBL7192168

C=Cc1c(C)c(C)c(C)c2ccccc12

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.36
TSHR P16473 4/20 0.35
ALDH1A1 P00352 3/20 0.35
L3MBTL1 Q9Y468 2/20 0.34
CYP3A4 P08684 1/20 0.34
HPGD P15428 1/20 0.34
MAPK1 P28482 1/20 0.34
CASP1 P29466 1/20 0.34
RAB9A P51151 1/20 0.34
CASP7 P55210 1/20 0.34
ATM Q13315 1/20 0.34
HIF1A Q16665 1/20 0.34
HSD17B10 Q99714 1/20 0.34
CYP2A6 P11509 4/20 0.33
NPC1 O15118 1/20 0.33
HSP90AA1 P07900 1/20 0.33
NPSR1 Q6W5P4 1/20 0.32
AHR P35869 1/20 0.32
TP53 P04637 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4646101 0.88 TSHR (0.40) CYP1A2TSHRALDH1A1L3MBTL1CYP3A4
SCHEMBL21012214 0.88 CYP1A2 (0.38) CYP1A2TSHRALDH1A1L3MBTL1CYP3A4
SCHEMBL31488756 0.88 TSHR (0.40) CYP1A2TSHRALDH1A1L3MBTL1CYP3A4
SCHEMBL22895187 0.84
SCHEMBL5248091 0.81 CYP1A2 (0.36) CYP1A2TSHRALDH1A1L3MBTL1CYP3A4
SCHEMBL9309858 0.80 ALDH1A1 (0.45) CYP1A2ALDH1A1MAPK1KDM4E
SCHEMBL3272269 0.79 PADI4 (0.48) CYP1A2TSHRALDH1A1L3MBTL1CYP3A4
SCHEMBL29925960 0.79 ALDH1A1 (0.45) CYP1A2TSHRALDH1A1MAPK1HSD17B10
SCHEMBL5831187 0.79 ALDH1A1 (0.45) CYP1A2TSHRALDH1A1MAPK1HSD17B10
SCHEMBL357443 0.79 CYP1A2 (0.53) CYP1A2TSHRALDH1A1L3MBTL1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6534595-B2 Blend of thermosetting resin, decomposable resin and solvent SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-03-18 US disclosed
US-20010038887-A1 Coating solution for forming porous organic film SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-11-08 US disclosed
US-5326489-A Sulfonated polymer NIPPON SHOKUBAI CO., LTD. (JP) 1994-07-05 US disclosed
EP-0523300-B1 Electrorheological fluids NIPPON CATALYTIC CHEM IND (JP) 1994-01-19 EP disclosed
EP-0529166-A1 Electrorheological fluids NIPPON SHOKUBAI CO., LTD. (JP) 1993-03-03 EP disclosed
EP-0523300-A1 Electrorheological fluids NIPPON SHOKUBAI KAGAKU KOGYO CO. LTD. (JP) 1993-01-20 EP disclosed