SCHEMBL3272629

SCHEMBL3272629

CCOC(=O)COC(=O)C(C)C1CCCC(C)(C)C1

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 2/20 0.37
KMT2A Q03164 1/20 0.36
UGT2B7 P16662 2/20 0.33
ALDH1A1 P00352 3/20 0.33
KDM4E B2RXH2 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
TSHR P16473 3/20 0.33
NPSR1 Q6W5P4 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
POLB P06746 1/20 0.31
NLRP3 Q96P20 1/20 0.31
CYP2D6 P10635 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23483380 0.90 ALDH1A1 (0.39) UGT2B7ALDH1A1KDM4ETSHRNPSR1
SCHEMBL3277864 0.88 CYP2C19 (0.33)
SCHEMBL22592975 0.83 ALDH1A1 (0.34) ALDH1A1TSHRNPSR1
SCHEMBL22592934 0.81 NAAA (0.32)
SCHEMBL22592933 0.81 NAAA (0.32)
SCHEMBL22592784 0.81 NAAA (0.32)
SCHEMBL22592809 0.81 NAAA (0.32)
SCHEMBL22592806 0.81 NAAA (0.32)
SCHEMBL3271470 0.81 KMT2A (0.45) EPHX2KMT2AALDH1A1TSHRNPSR1
SCHEMBL22592935 0.79 NAAA (0.36) EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7687452-B2 2-(3,3-dimethylcyclohexyl)propionic acid ethoxycarbonylmethyl ester; 1,5,5-trimethylspiro[2.5]octane-1-carboxylic acid ethoxycarbonylmethyl ester; new powerful musk odorants GIVAUDAN SA (CH) 2010-03-30 US claimed
EP-1743013-B1 ALICYCLIC CARBOXYLIC ACID OXYCARBONYLMETHYL ESTERS AND THEIR USE AS ODORANTS GIVAUDAN SA (CH) 2007-12-19 EP claimed
US-20070225201-A1 Organic Compounds GIVAUDAN SA (CH) 2007-09-27 US claimed
EP-1743013-A1 ALICYCLIC CARBOXYLIC ACID OXYCARBONYLMETHYL ESTERS AND THEIR USE AS ODORANTS Givaudan SA (CH) 2007-01-17 EP claimed
WO-2005108534-A1 ALICYCLIC CARBOXYLIC ACID OXYCARBONYLMETHYL ESTERS AND THEIR USE AS ODORANTS GIVAUDAN SA (CH) 2005-11-17 WO claimed
US-7687452-B2 2-(3,3-dimethylcyclohexyl)propionic acid ethoxycarbonylmethyl ester; 1,5,5-trimethylspiro[2.5]octane-1-carboxylic acid ethoxycarbonylmethyl ester; new powerful musk odorants GIVAUDAN SA (CH) 2010-03-30 US disclosed
EP-1743013-B1 ALICYCLIC CARBOXYLIC ACID OXYCARBONYLMETHYL ESTERS AND THEIR USE AS ODORANTS GIVAUDAN SA (CH) 2007-12-19 EP disclosed
US-20070225201-A1 Organic Compounds GIVAUDAN SA (CH) 2007-09-27 US disclosed
EP-1743013-A1 ALICYCLIC CARBOXYLIC ACID OXYCARBONYLMETHYL ESTERS AND THEIR USE AS ODORANTS Givaudan SA (CH) 2007-01-17 EP disclosed
WO-2005108534-A1 ALICYCLIC CARBOXYLIC ACID OXYCARBONYLMETHYL ESTERS AND THEIR USE AS ODORANTS GIVAUDAN SA (CH) 2005-11-17 WO disclosed