SCHEMBL3272676

SCHEMBL3272676

CCCO[SiH](OCCC)C1CC2C=CC1C2

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL295008 0.85 KDM4E (0.39) KDM4EALDH1A1
SCHEMBL27661449 0.84 KDM4E (0.38) KDM4EALDH1A1
SCHEMBL294325 0.75 KDM4E (0.34) KDM4EALDH1A1
SCHEMBL27661534 0.73 KDM4E (0.33) KDM4EALDH1A1
SCHEMBL5930981 0.71 KDM4E (0.37) KDM4EALDH1A1
SCHEMBL4742224 0.68 KDM4E (0.36) KDM4EALDH1A1
SCHEMBL3776428 0.68 KDM4E (0.37) KDM4EALDH1A1
SCHEMBL3750832 0.66 SMN1; SMN2 (0.34) ALDH1A1
SCHEMBL295642 0.66 KDM4E (0.33) KDM4EALDH1A1
SCHEMBL28151847 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7691919-B2 Dental materials based on ROMP composites IVOCLAR VIVADENT AG (LI) 2010-04-06 US disclosed
US-20070155922-A1 Process for producing cycloolefin addition polymer JSR CORPORATION (JP) 2007-07-05 US disclosed
EP-1555290-B1 Dental materials based on ROMP-composites IVOCLAR VIVADENT AG (LI) 2007-06-27 EP disclosed
EP-1712572-A1 PROCESS FOR PRODUCING CYCLOOLEFIN ADDITION POLYMER JSR Corporation (JP) 2006-10-18 EP disclosed
US-20050159510-A1 Dental materials based on ROMP composites IVOCLAR VIVADENT AG (LI) 2005-07-21 US disclosed
EP-1555290-A1 Dental materials based on ROMP-composites Ivoclar Vivadent AG (LI) 2005-07-20 EP disclosed