Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL295642 | 0.78 | KDM4E (0.33) | KDM4EALDH1A1 | |
| SCHEMBL6064274 | 0.75 | ALDH1A1 (0.36) | KDM4EALDH1A1LMNAGAATDP1 | |
| SCHEMBL294325 | 0.75 | KDM4E (0.34) | KDM4EALDH1A1LMNA | |
| SCHEMBL18830901 | 0.73 | KDM4E (0.31) | KDM4EALDH1A1LMNA | |
| SCHEMBL5930946 | 0.72 | KDM4E (0.33) | KDM4EALDH1A1 | |
| SCHEMBL295008 | 0.70 | KDM4E (0.39) | KDM4EALDH1A1 | |
| SCHEMBL5930981 | 0.68 | KDM4E (0.37) | KDM4EALDH1A1MEN1HTTKMT2A | |
| SCHEMBL3272676 | 0.68 | KDM4E (0.37) | KDM4EALDH1A1 | |
| SCHEMBL13517131 | 0.67 | KDM4E (0.32) | KDM4EALDH1A1LMNAGAATDP1 | |
| SCHEMBL24404787 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8436166-B2 | Amino-containing vinylsilane compounds and making method | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2013-05-07 | — | — | US | disclosed |
| US-20100317852-A1 | AMINO-CONTAINING VINYLSILANE COMPOUNDS AND MAKING METHOD | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2010-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317852-A1 | AMINO-CONTAINING VINYLSILANE COMPOUNDS AND MAKING METHOD | BHMT2, GNMT, VASP | KDM4E 285/4885ALDH1A1 4204/4885LMNA 2661/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.