Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3743323 | 0.82 | EPHX1 (0.33) | SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL3740657 | 0.80 | — | — | |
| SCHEMBL3748950 | 0.76 | ALDH1A1 (0.31) | SMN1; SMN2ALDH1A1TDP1 | |
| Propylene Oxide SCHEMBL28931166 | 0.71 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL3749024 | 0.69 | — | — | |
| SCHEMBL3741254 | 0.68 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL1169448 | 0.67 | CYP1A2 (0.31) | — | |
| SCHEMBL3272676 | 0.66 | KDM4E (0.37) | ALDH1A1 | |
| SCHEMBL1314192 | 0.65 | CYP1A2 (0.33) | — | |
| SCHEMBL28337884 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7834120-B2 | Monofunctional monomer having cage oligosiloxane structure and method of making | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2010-11-16 | — | — | US | disclosed |
| EP-1645560-B1 | Monofunctional monomer having cage oligosiloxane structure and method of making | SHINETSU CHEMICAL CO (JP) | 2008-05-28 | — | — | EP | disclosed |
| EP-1645560-A1 | Monofunctional monomer having cage oligosiloxane structure and method of making | Shin-Etsu Chemical Co., Ltd. (JP) | 2006-04-12 | — | — | EP | disclosed |
| US-20060074213-A1 | Monofunctional monomer having cage oligosiloxane structure and method of making | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2006-04-06 | — | — | US | disclosed |