⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3757214 | 0.98 | IDO1 (0.46) | — | |
| SCHEMBL219895 | 0.81 | TDP1 (0.61) | — | |
| SCHEMBL8795249 | 0.79 | SIGMAR1 (0.46) | — | |
| SCHEMBL1686500 | 0.79 | MEN1 (0.55) | — | |
| SCHEMBL30701164 | 0.75 | — | — | |
| SCHEMBL4776661 | 0.75 | — | — | |
| SCHEMBL5174781 | 0.75 | — | — | |
| SCHEMBL8072094 | 0.75 | — | — | |
| SCHEMBL5377783 | 0.75 | — | — | |
| SCHEMBL27902480 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101965350-A | Novel pyrazolo [3,4-d ] pyrimidine derivatives as anticancer agents | NATCO PHARMA LTD | 2011-02-02 | — | — | CN | claimed |
| US-3960566-A | Method for dry stabilization of silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JA) | 1976-06-01 | — | — | US | claimed |
| CN-118201919-A | Indole compounds and methods of use | 健赞公司 | 2024-06-14 | — | — | CN | disclosed |
| US-11827824-B2 | Condensed polycyclic conjugated polymers and their use for biological detection | AAT BIOQUEST, INC. (US) | 2023-11-28 | — | — | US | disclosed |
| US-11827824-B2 | Condensed polycyclic conjugated polymers and their use for biological detection | AAT BIOQUEST, INC. (US) | 2023-11-28 | — | — | US | disclosed |
| US-11220628-B2 | Condensed polycyclic conjugated polymers and their use for biological detection | AAT BIOQUEST, INC. (US) | 2022-01-11 | — | — | US | disclosed |
| EP-3459945-A1 | BCL-2/BCL-XL INHIBITORS FOR USE IN THE TREATMENT OF CANCER | The Regents of The University of Michigan (US) | 2019-03-27 | — | — | EP | disclosed |
| EP-2668180-B1 | BCL-2/BCL-XL INHIBITORS FOR USE IN THE TREATMENT OF CANCER | UNIV MICHIGAN REGENTS (US) | 2018-08-01 | — | — | EP | disclosed |
| EP-1924563-B1 | 11-BETA-HYDROXYSTEROID DEHYDROGENASE-1-INHIBITOR-DIABETES-TYPE 2-1 | HOFFMANN LA ROCHE (CH) | 2013-07-31 | — | — | EP | disclosed |
| EP-1924563-B1 | 11-BETA-HYDROXYSTEROID DEHYDROGENASE-1-INHIBITOR-DIABETES-TYPE 2-1 | HOFFMANN LA ROCHE (CH) | 2013-07-31 | — | — | EP | disclosed |
| US-8349847-B2 | Pyrazolo [3,4-D] pyrimidine derivatives as anti-cancer agents | KONAKANCHI DURGA PRASAD (IN) | 2013-01-08 | — | — | US | disclosed |
| EP-1612204-A1 | HYDRAZONE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-01-04 | — | — | EP | disclosed |
| EP-0614898-B1 | INDOLE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL USE THEREOF | TORAY INDUSTRIES (JP) | 2003-05-07 | — | — | EP | disclosed |
| US-6291470-B1 | DELTA-OPIOID ANTAGONIST HAVING HIGH SELECTIVITY AND ACTIVITY, THAT EXHIBITS IMMUNOSUPPRESSIVE ACTION, ANTIALLERGIC ACTION, ANTI-INFLAMMATORY ACTION AND BRAIN CELL-PROTECTING ACTION | TORAY INDUSTRIES, INC. (JP) | 2001-09-18 | — | — | US | disclosed |
| US-6087369-A | AN IMMUNOSUPPRESSIVE AGENT, ANTIALLERGIC AGENT, ANTI-INFLAMMATORY AGENT AND BRAIN CELL-PROTECTING AGENT | TORAY INDUSTRIES, LTD. (JP) | 2000-07-11 | — | — | US | disclosed |
| CN-1043766-C | Indole derivative and preparation and pharmaceutical using of same | TORAY INDUSTRIES (JP) | 1999-06-23 | — | — | CN | disclosed |
| US-5852030-A | Indole derivatives, process for producing the same and medicinal uses of the same | TORAY INDUSTRIES, INC. (JP) | 1998-12-22 | — | — | US | disclosed |
| CN-1092425-A | Indole derivatives, its manufacture method and medicinal use thereof | TORAY INDUSTRIES (JP) | 1994-09-21 | — | — | CN | disclosed |
| EP-0614898-A1 | INDOLE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 1994-09-14 | — | — | EP | disclosed |
| US-3960566-A | Method for dry stabilization of silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JA) | 1976-06-01 | — | — | US | disclosed |