Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL3273685

CCCCCC.O=C(O)C(F)(F)F

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FAAH O00519 12/20 0.61
CES1 P23141 9/20 0.58
CES2 O00748 7/20 0.58
MEN1 O00255 1/20 0.58
CYP1A2 P05177 1/20 0.58
KMT2A Q03164 1/20 0.58
HSD17B10 Q99714 1/20 0.58
EPHX1 P07099 1/20 0.52
AKR1B1 P15121 1/20 0.50
PLA2G6 O60733 1/20 0.48
ALDH1A1 P00352 1/20 0.48
TSHR P16473 1/20 0.48
SLC22A6 Q4U2R8 1/20 0.48
SLC22A8 Q8TCC7 1/20 0.48
GPR84 Q9NQS5 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tridecane SCHEMBL27500702 0.97 FAAH (0.62) FAAHCES1CES2MEN1CYP1A2
Octane SCHEMBL1123657 0.97 FAAH (0.62) FAAHCES1CES2MEN1CYP1A2
Dodecane SCHEMBL30416006 0.97 FAAH (0.62) FAAHCES1CES2MEN1CYP1A2
Octane SCHEMBL1696265 0.97 FAAH (0.62) FAAHCES1CES2MEN1CYP1A2
Nonane SCHEMBL4255344 0.97 FAAH (0.62) FAAHCES1CES2MEN1CYP1A2
Heptane SCHEMBL3935940 0.97 FAAH (0.62) FAAHCES1CES2MEN1CYP1A2
Hexadecane SCHEMBL4765353 0.97 FAAH (0.62) FAAHCES1CES2MEN1CYP1A2
Undecane SCHEMBL3628539 0.97 FAAH (0.62) FAAHCES1CES2MEN1CYP1A2
Trifluoroacetic Acid SCHEMBL28781369 0.97 FAAH (0.62) FAAHCES1CES2MEN1CYP1A2
Decane SCHEMBL3416451 0.97 FAAH (0.62) FAAHCES1CES2MEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110068616-B Normal phase chromatographic analysis method for 4-chlorine-2 nitrophenyl isocyanate and reaction liquid thereof 联化科技股份有限公司 2022-06-03 CN claimed
CN-110068616-A The normal-phase chromatography analysis method of chloro- 2 nitrophenyl isocyanate of 4- and its reaction solution 联化科技股份有限公司 2019-07-30 CN claimed
CN-115087652-B Heteroaromatic carboxamide derivatives as inhibitors of plasma kallikrein 勃林格殷格翰国际有限公司 2024-05-07 CN disclosed
CN-115461338-B 3-azabicyclo (3.1.0) hexane derivatives having KDM5 inhibitory activity and uses thereof 小野药品工业株式会社 2024-02-20 CN disclosed
CN-111971287-B Macrocyclic compounds as TRK kinase inhibitors 重庆复尚源创医药技术有限公司 2023-06-02 CN disclosed
CN-110944992-B Pharmaceutical compounds 赫普泰雅治疗有限公司 2023-05-16 CN disclosed
CN-116120287-A Heteroaromatic carboxamide derivatives as inhibitors of plasma kallikrein 勃林格殷格翰国际有限公司 2023-05-16 CN disclosed
CN-115461338-A 3-azabicyclo (3.1.0) hexane derivatives having KDM5 inhibitory activity and uses thereof 小野药品工业株式会社 2022-12-09 CN disclosed
CN-115087652-A Heteroaromatic carboxamide derivatives as plasma kallikrein inhibitors 勃林格殷格翰国际有限公司 2022-09-20 CN disclosed
CN-115052873-A Heteroaromatic carboxamide derivatives as plasma kallikrein inhibitors 勃林格殷格翰国际有限公司 2022-09-13 CN disclosed
CN-110068616-B Normal phase chromatographic analysis method for 4-chlorine-2 nitrophenyl isocyanate and reaction liquid thereof 联化科技股份有限公司 2022-06-03 CN disclosed
CN-1154642-C Compounds for the treatment of retroviral infections �������Ŷ���Լ��������˾ 2004-06-23 CN disclosed
CN-1395562-A Nitrogenous cyclic compounds and pharmaceutical compositions containing the same EISAI CO LTD (JP) 2003-02-05 CN disclosed
EP-1254895-A1 NITROGENOUS CYCLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME Eisai Co., Ltd. (JP) 2002-11-06 EP disclosed
EP-1216980-A1 CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME Eisai Co., Ltd. (JP) 2002-06-26 EP disclosed
US-5719308-A Enzymatic process for the preparation of optically active tetralin derivatives SANOFI (FR) 1998-02-17 US disclosed
CN-1150424-A Compounds for the treatment of retroviral infections UPJOHN CO (US) 1997-05-21 CN disclosed
US-5573949-A Enzymatic process for the preparation of optically active Tetrahydro-2-naphthoic acids SANOFI (FR) 1996-11-12 US disclosed
EP-0552254-A1 CRYSTALLIZATION OF OPTICAL ISOMERS OF LEUKOTRIENE ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 1993-07-28 EP disclosed
WO-1992005151-A1 CRYSTALLIZATION OF OPTICAL ISOMERS OF LEUKOTRIENE ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 1992-04-02 WO disclosed