Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 5/20 | 0.77 |
| ▸ | MAPT | P10636 | 3/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.77 |
| ▸ | MEN1 | O00255 | 2/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.77 |
| ▸ | TP53 | P04637 | 1/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.77 |
| ▸ | PKM | P14618 | 1/20 | 0.77 |
| ▸ | CDC25A | P30304 | 1/20 | 0.77 |
| ▸ | CDC25B | P30305 | 1/20 | 0.77 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.77 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.77 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.77 |
| ▸ | APAF1 | O14727 | 2/20 | 0.57 |
| ▸ | TDP2 | O95551 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lapachol SCHEMBL31492698 | 0.98 | DHODH (0.79) | DHODHMAPTKDM4EMEN1KMT2A | |
| Lapachol SCHEMBL157255 | 0.98 | DHODH (0.79) | DHODHMAPTKDM4EMEN1KMT2A | |
| Lapachol SCHEMBL18769814 | 0.97 | DHODH (0.77) | DHODHMAPTKDM4EMEN1KMT2A | |
| Lapachol SCHEMBL18037006 | 0.91 | DHODH (0.68) | DHODHMAPTKDM4EMEN1KMT2A | |
| Lapachol SCHEMBL7362189 | 0.90 | MAPT (0.67) | DHODHMAPTKDM4EMEN1KMT2A | |
| Lapachol SCHEMBL28491462 | 0.88 | DHODH (0.65) | DHODHMAPTKDM4EMEN1KMT2A | |
| SCHEMBL157256 | 0.87 | DHODH (1.00) | DHODHMAPTKDM4EMEN1KMT2A | |
| SCHEMBL14236459 | 0.86 | DHODH (0.66) | DHODHMAPTKDM4EMEN1KMT2A | |
| SCHEMBL20811074 | 0.86 | DHODH (0.70) | DHODHMAPTKDM4EMEN1KMT2A | |
| SCHEMBL974935 | 0.85 | MAPT (0.74) | DHODHMAPTKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7691418-B2 | Composition for inhibiting or preventing the formation of a biofilm | OYSTERSHELL NV (BE) | 2010-04-06 | — | — | US | disclosed |
| US-20070258913-A1 | Composition for Inhibiting or Preventing the Formation of a Biofilm | OYSTERSHELL NV (BE) | 2007-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070258913-A1 | Composition for Inhibiting or Preventing the Formation of a Biofilm | NQO2, NFKBIA, CROCC | DHODH 547/4885MAPT 4695/4885KDM4E 3950/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.