Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12676069 | 0.93 | NR3C1 (0.66) | NR3C1PGR | |
| SCHEMBL12676347 | 0.90 | NR3C1 (0.80) | NR3C1PGR | |
| SCHEMBL3274139 | 0.90 | NR3C1 (0.82) | NR3C1PGR | |
| SCHEMBL13617694 | 0.90 | NR3C1 (0.80) | NR3C1PGR | |
| SCHEMBL3278415 | 0.89 | NR3C1 (0.77) | NR3C1PGR | |
| SCHEMBL16568778 | 0.89 | NR3C1 (0.77) | NR3C1PGR | |
| SCHEMBL3149516 | 0.88 | NR3C1 (0.68) | NR3C1PGR | |
| SCHEMBL3275674 | 0.88 | NR3C1 (0.56) | NR3C1PGR | |
| SCHEMBL1456275 | 0.85 | NR3C1 (1.00) | NR3C1PGR | |
| SCHEMBL1457090 | 0.85 | NR3C1 (1.00) | NR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9738632-B2 | Phenyl and benzodioxinyl substituted indazoles derivatives | ASTRAZENECA AB (SE) | 2017-08-22 | — | — | US | disclosed |
| US-9738632-B2 | Phenyl and benzodioxinyl substituted indazoles derivatives | ASTRAZENECA AB (SE) | 2017-08-22 | — | — | US | disclosed |
| US-9738632-B2 | Phenyl and benzodioxinyl substituted indazoles derivatives | ASTRAZENECA AB (SE) | 2017-08-22 | — | — | US | disclosed |
| US-20170081315-A1 | Phenyl and benzodioxinyl substituted indazoles derivatives | ASTRAZENECA AB (SE) | 2017-03-23 | — | — | US | disclosed |
| US-20170081315-A1 | Phenyl and benzodioxinyl substituted indazoles derivatives | ASTRAZENECA AB (SE) | 2017-03-23 | — | — | US | disclosed |
| US-20170081315-A1 | Phenyl and benzodioxinyl substituted indazoles derivatives | ASTRAZENECA AB (SE) | 2017-03-23 | — | — | US | disclosed |
| US-9512110-B2 | Phenyl and benzodioxinyl substituted indazoles derivatives | ASTRAZENECA AB (SE) | 2016-12-06 | — | — | US | disclosed |
| US-9512110-B2 | Phenyl and benzodioxinyl substituted indazoles derivatives | ASTRAZENECA AB (SE) | 2016-12-06 | — | — | US | disclosed |
| US-9512110-B2 | Phenyl and benzodioxinyl substituted indazoles derivatives | ASTRAZENECA AB (SE) | 2016-12-06 | — | — | US | disclosed |
| EP-2291369-B1 | BENZODIOXINYL SUBSTITUTED INDAZOLE DERIVATIVES | ASTRAZENECA AB (SE) | 2015-11-04 | — | — | EP | disclosed |
| EP-2620435-A1 | Phenyl and benzodioxinyl substituted indazole derivatives | Astrazeneca AB (SE) | 2013-07-31 | — | — | EP | disclosed |
| EP-2620435-A1 | Phenyl and benzodioxinyl substituted indazole derivatives | Astrazeneca AB (SE) | 2013-07-31 | — | — | EP | disclosed |
| US-20120302617-A1 | Phenyl and Benzodioxinyl Substituted Indazoles Derivatives | ASTRAZENECA AB (SE) | 2012-11-29 | — | — | US | disclosed |
| US-8211930-B2 | Phenyl and benzodioxinyl substituted indazoles derivatives | ASTRAZENECA AB (SE) | 2012-07-03 | — | — | US | disclosed |
| US-8211930-B2 | Phenyl and benzodioxinyl substituted indazoles derivatives | ASTRAZENECA AB (SE) | 2012-07-03 | — | — | US | disclosed |
| US-8211930-B2 | Phenyl and benzodioxinyl substituted indazoles derivatives | ASTRAZENECA AB (SE) | 2012-07-03 | — | — | US | disclosed |
| US-20100087489-A1 | Phenyl and Benzodioxinyl Substituted Indazoles Derivatives | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2010-04-08 | — | — | US | disclosed |
| US-20100087489-A1 | Phenyl and Benzodioxinyl Substituted Indazoles Derivatives | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2010-04-08 | — | — | US | disclosed |
| US-20100087489-A1 | Phenyl and Benzodioxinyl Substituted Indazoles Derivatives | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2010-04-08 | — | — | US | disclosed |
| WO-2009142571-A1 | PHENYL AND BENZODIOXINYL SUBSTITUTED INDAZOLES DERIVATIVES | ASTRAZENECA AB (SE) | 2009-11-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120302617-A1 | Phenyl and Benzodioxinyl Substituted Indazoles Derivatives | CYP3A5, CYP4X1, CYP3A7 | NR3C1 1959/4885PGR 390/4885 |
| US-20100087489-A1 | Phenyl and Benzodioxinyl Substituted Indazoles Derivatives | CYP3A5, ABCB1, CYP4X1 | NR3C1 1496/4885PGR 315/4885 |
| US-20170081315-A1 | Phenyl and benzodioxinyl substituted indazoles derivatives | CYP3A5, ABCB1, CYP4X1 | NR3C1 1496/4885PGR 315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.