Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 15/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 14/20 | 0.44 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL35186 | 0.85 | NR1H2 (0.45) | NR1H2NR1H3 | |
| SCHEMBL2829190 | 0.75 | HAVCR2 (0.55) | NR1H2NR1H3HAVCR2PPARGPPARD | |
| SCHEMBL2719771 | 0.74 | PIK3CD (0.43) | NR1H2NR1H3HAVCR2NR4A2LMNA | |
| SCHEMBL11555903 | 0.73 | CYP1A2 (0.42) | LMNA | |
| SCHEMBL23479346 | 0.72 | NR4A2 (0.56) | NR1H2NR1H3HAVCR2NR4A2LMNA | |
| SCHEMBL28782863 | 0.71 | GRM5 (0.54) | NR1H2NR1H3HAVCR2 | |
| SCHEMBL29712654 | 0.71 | GRM5 (0.54) | NR1H2NR1H3HAVCR2 | |
| SCHEMBL20466853 | 0.69 | ATM (0.38) | LMNA | |
| SCHEMBL1125326 | 0.69 | NR1H2 (0.47) | NR1H2NR1H3HAVCR2NR4A2PPARG | |
| SCHEMBL35232 | 0.69 | NR1H2 (0.61) | NR1H2NR1H3HAVCR2PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590948-A1 | NOVEL QUINOLINE ESTERS USEFUL FOR TREATING SKIN DISORDERS | Wyeth LLC (US) | 2013-05-15 | — | — | EP | disclosed |
| WO-2012004748-A1 | NOVEL QUINOLINE ESTERS USEFUL FOR TREATING SKIN DISORDERS | WYETH LLC (US) | 2012-01-12 | — | — | WO | disclosed |