Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | LIPE | Q05469 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30847603 | 0.91 | SMN1; SMN2 (0.60) | SMN1; SMN2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL5650138 | 0.89 | RAB9A (0.71) | SMN1; SMN2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL5649397 | 0.81 | RAB9A (0.64) | SMN1; SMN2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL5649783 | 0.80 | RAB9A (0.62) | SMN1; SMN2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL5650588 | 0.80 | RAB9A (0.70) | SMN1; SMN2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL3276088 | 0.79 | RAB9A (0.75) | SMN1; SMN2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL5650031 | 0.78 | LIPE (0.57) | SMN1; SMN2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL30738654 | 0.77 | RAB9A (0.73) | SMN1; SMN2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL5650101 | 0.77 | RAB9A (0.59) | SMN1; SMN2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL25270458 | 0.76 | SMN1; SMN2 (0.71) | SMN1; SMN2RAB9ANPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7696374-B2 | Arylalklcarbamate derivatives, preparation method thereof and use of same in therapeutics | SANOFI-AVENTIS (FR) | 2010-04-13 | — | — | US | disclosed |
| US-20060223805-A1 | Arylalklcarbamate derivatives, preparation method thereof and use of same in therapeutics | SANOFI-AVENTIS (FR) | 2006-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060223805-A1 | Arylalklcarbamate derivatives, preparation method thereof and use of same in therapeutics | GBA1, NAT1, AADAC | SMN1; SMN2 3208/4885RAB9A 1781/4885NPC1 45/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.