Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18970888 | 0.89 | KDM4E (0.51) | ALDH1A1SLC22A1ADRB2ADRB1LMNA | |
| SCHEMBL13384657 | 0.83 | P2RX3 (0.42) | RORCP2RX3ALDH1A1SLC22A1ADRB2 | |
| SCHEMBL3279217 | 0.81 | RORC (0.50) | RORCP2RX3ALDH1A1L3MBTL1NPC1 | |
| SCHEMBL3274226 | 0.80 | RORC (0.63) | RORCP2RX3ALDH1A1 | |
| SCHEMBL15004586 | 0.80 | P2RX3 (0.38) | RORCP2RX3SLC22A1ADRB2ADRB1 | |
| SCHEMBL3278981 | 0.80 | P2RX3 (0.40) | RORCP2RX3ALDH1A1SLC22A1ADRB2 | |
| SCHEMBL13403337 | 0.79 | RORC (0.48) | RORCP2RX3ALDH1A1NPC1RAB9A | |
| SCHEMBL7326435 | 0.77 | RORC (0.52) | RORCCASP3ALDH1A1SLC22A1ADRB2 | |
| SCHEMBL27766069 | 0.77 | RORC (0.46) | RORCP2RX3ALDH1A1LMNANPC1 | |
| SCHEMBL3274109 | 0.76 | RORC (0.46) | RORCP2RX3ALDH1A1L3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103601758-B | ruthenium-based catalytic complexes and use of such complexes for olefin metathesis | 尤米科尔股份公司及两合公司 | 2017-09-08 | — | — | CN | disclosed |
| EP-2476688-B1 | Ruthenium-based catalytic complexes and the use of such complexes for olefin metathesis | UMICORE AG & CO KG (DE) | 2017-06-14 | — | — | EP | disclosed |
| EP-2476688-B1 | Ruthenium-based catalytic complexes and the use of such complexes for olefin metathesis | UMICORE AG & CO KG (DE) | 2017-06-14 | — | — | EP | disclosed |
| EP-2097431-B1 | RUTHENIUM-BASED CATALYTIC COMPLEXES AND THE USE OF SUCH COMPLEXES FOR OLEFIN METATHESIS | UMICORE AG & CO KG (DE) | 2015-03-25 | — | — | EP | disclosed |
| EP-2097431-B1 | RUTHENIUM-BASED CATALYTIC COMPLEXES AND THE USE OF SUCH COMPLEXES FOR OLEFIN METATHESIS | UMICORE AG & CO KG (DE) | 2015-03-25 | — | — | EP | disclosed |
| CN-101595116-B | Ruthenium-based catalytic complexes and use of such complexes for olefin metathesis | ECOLE NALE SUP ARTES METIERS | 2014-08-06 | — | — | CN | disclosed |
| CN-103601758-A | Ruthenium-based catalytic complexes and use of such complexes for olefin metathesis | UMICORE AG & CO KG | 2014-02-26 | — | — | CN | disclosed |
| US-8586757-B2 | Ruthenium-based catalytic complexes and the use of such complexes for olefin metathesis | UMICORE AG & CO. KG (DE) | 2013-11-19 | — | — | US | disclosed |
| US-8586757-B2 | Ruthenium-based catalytic complexes and the use of such complexes for olefin metathesis | UMICORE AG & CO. KG (DE) | 2013-11-19 | — | — | US | disclosed |
| US-20130144060-A1 | Ruthenium-Based Catalytic Complexes and the Use of Such Complexes for Olefin Metathesis | UMICORE AG & CO. KG (DE) | 2013-06-06 | — | — | US | disclosed |
| US-8394965-B2 | Ruthenium-based catalytic complexes and the use of such complexes for olefin metathesis | UMICORE AG & CO. KG (DE) | 2013-03-12 | — | — | US | disclosed |
| US-8394965-B2 | Ruthenium-based catalytic complexes and the use of such complexes for olefin metathesis | UMICORE AG & CO. KG (DE) | 2013-03-12 | — | — | US | disclosed |
| US-8394965-B2 | Ruthenium-based catalytic complexes and the use of such complexes for olefin metathesis | UMICORE AG & CO. KG (DE) | 2013-03-12 | — | — | US | disclosed |
| EP-2476688-A1 | Ruthenium-based catalytic complexes and the use of such complexes for olefin metathesis | Umicore AG & Co. KG (DE) | 2012-07-18 | — | — | EP | disclosed |
| EP-2476688-A1 | Ruthenium-based catalytic complexes and the use of such complexes for olefin metathesis | Umicore AG & Co. KG (DE) | 2012-07-18 | — | — | EP | disclosed |
| US-20100087644-A1 | RUTHENIUM-BASED CATALYTIC COMPLEXES AND THE USE OF SUCH COMPLEXES FOR OLEFIN METATHESIS | ECOLE NATIONALE SUPERIEURE DE CHIMIE DE RENNES (FR) | 2010-04-08 | — | — | US | disclosed |
| US-20100087644-A1 | RUTHENIUM-BASED CATALYTIC COMPLEXES AND THE USE OF SUCH COMPLEXES FOR OLEFIN METATHESIS | ECOLE NATIONALE SUPERIEURE DE CHIMIE DE RENNES (FR) | 2010-04-08 | — | — | US | disclosed |
| US-20100087644-A1 | RUTHENIUM-BASED CATALYTIC COMPLEXES AND THE USE OF SUCH COMPLEXES FOR OLEFIN METATHESIS | ECOLE NATIONALE SUPERIEURE DE CHIMIE DE RENNES (FR) | 2010-04-08 | — | — | US | disclosed |
| CN-101595116-A | Ruthenium-based catalytic complexes and use of such complexes for olefin metathesis | ENSCR (FR) | 2009-12-02 | — | — | CN | disclosed |
| WO-2008065187-A1 | RUTHENIUM-BASED CATALYTIC COMPLEXES AND THE USE OF SUCH COMPLEXES FOR OLEFIN METATHESIS | ECOLE NATIONALE SUPERIEURE DE CHIMIE DE RENNES (FR) | 2008-06-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087644-A1 | RUTHENIUM-BASED CATALYTIC COMPLEXES AND THE USE OF SUCH COMPLEXES FOR OLEFIN METATHESIS | CYC1, C1S, C5 | RORC 3977/4885P2RX3 1799/4885CASP3 2612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.