Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | OXTR | P30559 | 2/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16373744 | 0.86 | POLB (0.57) | KMT2AMEN1ALDH1A1POLBPKM | |
| SCHEMBL17788525 | 0.83 | POLB (0.52) | KMT2AMEN1ALDH1A1POLBPKM | |
| SCHEMBL2752484 | 0.80 | POLB (0.51) | KMT2AMEN1ALDH1A1POLBPKM | |
| SCHEMBL16606327 | 0.80 | MAPT (0.58) | KMT2AMEN1ALDH1A1POLBPKM | |
| SCHEMBL28476929 | 0.77 | OXTR (0.50) | KMT2AMEN1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL28473802 | 0.77 | OXTR (0.50) | KMT2AMEN1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL28473805 | 0.77 | OXTR (0.50) | KMT2AMEN1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL2128245 | 0.76 | POLB (0.47) | KMT2AMEN1ALDH1A1POLBPKM | |
| SCHEMBL2130432 | 0.74 | POLB (0.45) | KMT2AMEN1ALDH1A1POLBPKM | |
| SCHEMBL28485014 | 0.72 | MAPT (0.44) | KMT2AMEN1ALDH1A1POLBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8133474-B2 | Porphyrin chelate compound that may be complexed with zinc, manganese, magnesium, iron or aluminum; capable of insertion into cell; zinc, calcium, mercury, cadmium, and lead analytes; determining shift in signal; medical diagnosis | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-03-13 | — | — | US | disclosed |
| US-20080138292-A1 | Sensors for fluorescence and magnetic resonance imaging | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080138292-A1 | Sensors for fluorescence and magnetic resonance imaging | CA2, SLC30A6, SLC39A3 | KMT2A 3742/4885MEN1 236/4885ALDH1A1 3462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.