Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 4/20 | 0.49 |
| ▸ | CA2 | P00918 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11347496 | 0.88 | HDAC3 (0.51) | HRH3CA1CA2MAPTMEN1 | |
| SCHEMBL22677533 | 0.84 | HDAC3 (0.54) | HRH3CA1CA2MAPTMEN1 | |
| SCHEMBL5281377 | 0.84 | HDAC3 (0.54) | HRH3CA1CA2MAPTMEN1 | |
| SCHEMBL1924747 | 0.83 | MAPT (0.57) | CA1CA2MAPTMEN1KMT2A | |
| SCHEMBL4268165 | 0.83 | MEN1 (0.59) | CA1CA2MAPTMEN1KMT2A | |
| SCHEMBL8025764 | 0.82 | CA1 (0.46) | HRH3CA1CA2MAPTMEN1 | |
| SCHEMBL25557821 | 0.81 | HDAC3 (0.48) | HRH3CA1CA2MAPTMEN1 | |
| SCHEMBL13167595 | 0.81 | HRH3 (0.49) | HRH3CA1CA2MAPTMEN1 | |
| SCHEMBL12781694 | 0.81 | HRH3 (0.49) | HRH3CA1CA2MAPTMEN1 | |
| SCHEMBL1950603 | 0.81 | HRH3 (0.49) | HRH3CA1CA2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11840527-B2 | Non-fused thiophene derivatives and their uses | ENYO PHARMA (FR) | 2023-12-12 | — | — | US | disclosed |
| EP-2197981-A2 | GREEN LUMINESCENT MATERIALS | E. I. Du Pont de Nemours and Company (US) | 2010-06-23 | — | — | EP | disclosed |
| WO-2008150828-A2 | GREEN LUMINESCENT MATERIALS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11840527-B2 | Non-fused thiophene derivatives and their uses | FTH1, SLC40A1, FECH | HRH3 4237/4885CA1 4832/4885CA2 3530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.