⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3284871 | 0.88 | ALDH1A1 (0.58) | — | |
| SCHEMBL6848665 | 0.78 | — | — | |
| SCHEMBL5804490 | 0.78 | — | — | |
| SCHEMBL8146532 | 0.78 | ALDH1A1 (0.54) | — | |
| SCHEMBL348694 | 0.77 | — | — | |
| SCHEMBL27964995 | 0.77 | ALDH1A1 (0.55) | — | |
| SCHEMBL9411152 | 0.75 | ALDH1A1 (0.41) | — | |
| SCHEMBL467449 | 0.75 | — | — | |
| SCHEMBL19133767 | 0.74 | ALDH1A1 (0.45) | — | |
| SCHEMBL11060991 | 0.74 | ALDH1A1 (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2473486-B2 | PYRIMIDINES AS HEPCIDINE ANTAGONISTS | VIFOR INT AG (CH) | 2021-09-22 | — | — | EP | disclosed |
| EP-2473486-B1 | PYRIMIDINES AS HEPCIDINE ANTAGONISTS | VIFOR INT AG (CH) | 2015-10-28 | — | — | EP | disclosed |
| CN-101370773-B | Cycloalkanecarboxamide derivative and method for producing same | SEIKAGAKU KOGYO CO LTD | 2014-04-09 | — | — | CN | disclosed |
| EP-2591023-A2 | DEGRADABLE SUPERABSORBENT POLYMERS | Reluceo Inc. (US) | 2013-05-15 | — | — | EP | disclosed |
| US-20130065765-A1 | DEGRADABLE SUPERABSORBENT POLYMERS | RELUCEO, INC. | 2013-03-14 | — | — | US | disclosed |
| US-20120214798-A1 | Novel Ethanediamone Hepcidine Antagonists | VIFOR (INTERNATIONAL) AG (CH) | 2012-08-23 | — | — | US | disclosed |
| US-20120202806-A1 | Novel Pyrimidine- And Triazine-Hepcidine Antagonists | VIFOR (INTERNATIONAL) AG (CH) | 2012-08-09 | — | — | US | disclosed |
| EP-2475643-A1 | NOVEL ETHANE DIAMINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2012-07-18 | — | — | EP | disclosed |
| EP-2473486-A1 | NOVEL PYRIMIDINE AND TRIAZINE HEPCIDINE ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2012-07-11 | — | — | EP | disclosed |
| WO-2012006278-A2 | DEGRADABLE SUPERABSORBENT POLYMERS | RELUCEO, INC. (US) | 2012-01-12 | — | — | WO | disclosed |
| WO-2011026959-A1 | NOVEL ETHANE DIAMINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2011-03-10 | — | — | WO | disclosed |
| WO-2011023722-A1 | NOVEL QUINOXALINONE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2011-03-03 | — | — | WO | disclosed |
| CN-101370773-A | Cycloalkanecarboxamide derivative and method for producing same | SEIKAGAKU KOGYO CO LTD (JP) | 2009-02-18 | — | — | CN | disclosed |
| US-5733948-A | EXPOSING ACRYLATE-CONTAINING PHOTOPOLYMER RESIN TO ACTINIC RADIATION, DEVELOPING | MAC DERMID, IMAGING TECHNOLOGY, INC. (US) | 1998-03-31 | — | — | US | disclosed |
| EP-0601184-A1 | FUSED PYRIDAZINE COMPOUND AND PHARMACEUTICAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-06-15 | — | — | EP | disclosed |
| US-4576753-A | MICROBIOCIDES, ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-03-18 | — | — | US | disclosed |
| US-4472309-A | ANTIMICROBIAL | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-09-18 | — | — | US | disclosed |
| US-4304718-A | ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-12-08 | — | — | US | disclosed |
| US-4264498-A | REACTED WITH AN ACID, ITS ACID HALIDE, OR ANHYDRIDE IN THE PRESENCE OF BORON TRIHALIDE AND AN ORGANIC BASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-04-28 | — | — | US | disclosed |
| US-4181800-A | ANTIBIOTICS FROM SUBSTITUTED PERHYDRO-S-TRIAZINES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-01-01 | — | — | US | disclosed |