Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL114542 | 0.82 | TRPV4 (0.58) | TRPV4CA12CA1CA2CA4 | |
| SCHEMBL29421253 | 0.82 | TRPV4 (0.58) | TRPV4CA12CA1CA2CA4 | |
| Methane SCHEMBL28831878 | 0.80 | TRPV4 (0.56) | TRPV4CA12CA1CA2CA4 | |
| SCHEMBL18151424 | 0.79 | MLYCD (0.43) | TRPV4CA12CA1CA2CA4 | |
| SCHEMBL21675704 | 0.78 | KDM4E (0.40) | TRPV4CA12CA1CA2CA4 | |
| SCHEMBL26511108 | 0.78 | TRPV4 (0.43) | TRPV4CA12CA1CA2CA4 | |
| SCHEMBL26504398 | 0.75 | TRPV4 (0.41) | TRPV4CA12CA1CA2CA4 | |
| SCHEMBL2367892 | 0.73 | KDM4E (0.46) | TRPV4CA12CA1CA2CA4 | |
| SCHEMBL30004124 | 0.73 | KDM4E (0.46) | TRPV4CA12CA1CA2CA4 | |
| SCHEMBL29177287 | 0.72 | PTGS1 (0.36) | TRPV4CA12CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7696129-B2 | Substituted aromatic amide derivative, intermediate thereof, agrohorticultural insecticide containing thereof and method for the use thereof | NIHON NOHYAKU CO., LTD. (JP) | 2010-04-13 | — | — | US | disclosed |
| CN-100443467-C | Substituted aromatic amide derivative intemediate thereof, agrohorticultral insecticide containing thereof and method for use thereof | NIHON NOHYAKU CO LTD (JP) | 2008-12-17 | — | — | CN | disclosed |
| EP-1390342-B1 | SUBSTITUTED AROMATIC AMIDE DERIVATIVES, INTERMEDIATES THEREOF, AGROHORTICULTURAL INSECTICIDE CONTAINING THEREOF AND METHOD FOR THE USE THEREOF | NIHON NOHYAKU CO LTD (JP) | 2007-10-31 | — | — | EP | disclosed |
| US-20040152598-A1 | Substituted aromatic amide derivative, intermediate thereof, agrohorticultural insecticide containing thereof and method for the use thereof | GOTO MAKOTO (JP) | 2004-08-05 | — | — | US | disclosed |
| CN-1509268-A | Substituted aromatic amide derivative intemediate thereof, agrohorticultral insecticide containing thereof and method for use thereof | �ձ��ݶ�ũҩ��ʽ���� | 2004-06-30 | — | — | CN | disclosed |
| EP-1390342-A2 | SUBSTITUTED AROMATIC AMIDE DERIVATIVE, INTERMEDIATE THEREOF, AGROHORTICULTURAL INSECTICIDE CONTAINING THEREOF AND METHOD FOR THE USE THEREOF | Nihon Nohyaku Co., Ltd. (JP) | 2004-02-25 | — | — | EP | disclosed |
| WO-2002094765-A2 | SUBSTITUTED AROMATIC AMIDE DERIVATIVE, INTERMEDIATE THEREOF, AGROHORTICULTURAL INSECTICIDE CONTAINING THEREOF AND METHOD FOR THE USE THEREOF | NIHON NOHYAKU CO., LTD. (JP) | 2002-11-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040152598-A1 | Substituted aromatic amide derivative, intermediate thereof, agrohorticultural insecticide containing thereof and method for the use thereof | CYP4B1, CYP4F2, CYP4F8 | TRPV4 2274/4885CA12 4315/4885CA1 2112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.