Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MMP3 | P08254 | 5/20 | 0.53 |
| ▸ | MMP1 | P03956 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | MMP13 | P45452 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
| ▸ | HRH2 | P25021 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | ACR | P10323 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13384900 | 0.89 | LMNA (0.58) | MMP2ALDH1A1MAPTMMP3MMP1 | |
| SCHEMBL5881164 | 0.89 | LMNA (0.58) | MMP2ALDH1A1MAPTMMP3MMP1 | |
| SCHEMBL13632500 | 0.89 | MMP2 (0.56) | MMP2ALDH1A1MAPTMMP3MMP1 | |
| SCHEMBL12736327 | 0.86 | MAPT (0.57) | MMP2ALDH1A1MAPTMMP3MMP1 | |
| SCHEMBL5881168 | 0.86 | MAPT (0.57) | MMP2ALDH1A1MAPTMMP3MMP1 | |
| SCHEMBL14132234 | 0.86 | NPC1 (0.63) | ALDH1A1MAPTMMP3HDAC1HDAC2 | |
| SCHEMBL3434932 | 0.86 | NPC1 (0.63) | ALDH1A1MAPTMMP3HDAC1HDAC2 | |
| SCHEMBL10604715 | 0.86 | NPC1 (0.63) | ALDH1A1MAPTMMP3HDAC1HDAC2 | |
| SCHEMBL8621621 | 0.86 | NPC1 (0.63) | ALDH1A1MAPTMMP3HDAC1HDAC2 | |
| SCHEMBL5881229 | 0.86 | NPC1 (0.63) | ALDH1A1MAPTMMP3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8562863-B2 | Cholesteric glassy liquid crystals with hybrid chiral-nematic mesogens | THE UNIVERSITY OF ROCHESTER (US) | 2013-10-22 | — | — | US | disclosed |
| US-20100086704-A1 | CHOLESTERIC GLASSY LIQUID CRYSTALS WITH HYBRID CHIRAL-NEMATIC MESOGENS | THE UNIVERSITY OF ROCHESTER | 2010-04-08 | — | — | US | disclosed |
| US-7001648-B2 | Glassy chiral-nematic liquid crystals and optical devices containing same | UNIVERSITY OF ROCHESTER (US) | 2006-02-21 | — | — | US | disclosed |
| US-20050263741-A1 | GLASSY CHIRAL-NEMATIC LIQUID CRYSTALS AND OPTICAL DEVICES CONTAINING SAME | NATIONAL SCIENCE FOUNDATION | 2005-12-01 | — | — | US | disclosed |