Juarezic Acid

Juarezic Acid

SCHEMBL3276072

CCC=C(C)C(=O)O.O=C(O)C=CC=Cc1ccccc1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 2/20 0.47
HDAC4 P56524 2/20 0.47
HDAC1 Q13547 2/20 0.47
HDAC7 Q8WUI4 2/20 0.47
HDAC2 Q92769 2/20 0.47
HDAC10 Q969S8 2/20 0.47
HDAC11 Q96DB2 2/20 0.47
HDAC8 Q9BY41 2/20 0.47
HDAC6 Q9UBN7 2/20 0.47
HDAC9 Q9UKV0 2/20 0.47
HDAC5 Q9UQL6 2/20 0.47
TNKS O95271 1/20 0.47
HCAR2 Q8TDS4 1/20 0.47
TNKS2 Q9H2K2 1/20 0.47
AKR1C3 P42330 1/20 0.45
GLA P06280 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
MAOB P27338 6/20 0.44
ESR1 P03372 2/20 0.43
PGR P06401 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Juarezic Acid SCHEMBL1172553 0.84 HDAC3 (0.53) HDAC3HDAC4HDAC1HDAC7HDAC2
Juarezic Acid SCHEMBL28980693 0.82 HDAC3 (0.63) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL476359 0.82 AKR1C3 (0.41) HDAC3HDAC4HDAC1HDAC7HDAC2
Juarezic Acid SCHEMBL11522747 0.80 HDAC3 (0.71) HDAC3HDAC4HDAC1HDAC7HDAC2
Juarezic Acid SCHEMBL474728 0.80 HDAC3 (0.71) HDAC3HDAC4HDAC1HDAC7HDAC2
Juarezic Acid SCHEMBL144680 0.80 HDAC3 (0.71) HDAC3HDAC4HDAC1HDAC7HDAC2
Juarezic Acid SCHEMBL144681 0.80 HDAC3 (0.71) HDAC3HDAC4HDAC1HDAC7HDAC2
Juarezic Acid SCHEMBL15119 0.80 HDAC3 (0.71) HDAC3HDAC4HDAC1HDAC7HDAC2
Juarezic Acid SCHEMBL436113 0.80 HDAC3 (0.71) HDAC3HDAC4HDAC1HDAC7HDAC2
Juarezic Acid SCHEMBL1456940 0.80 HDAC3 (0.55) HDAC3HDAC4HDAC1HDAC7HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100328388-A1 INKJET PRINTER, INKJET PRINTING METHOD AND PROGRAM CANON KABUSHIKI KAISHA (JP) 2010-12-30 US disclosed
EP-2266803-A1 Inkjet printer, inkjet printing method and program Canon Kabushiki Kaisha (JP) 2010-12-29 EP disclosed
US-7695090-B2 Ink jet printing apparatus, method for determining print medium, and method for determining ink ejection amount CANON KABUSHIKI KAISHA (JP) 2010-04-13 US disclosed
US-20070206039-A1 INK JET PRINTING APPARATUS, METHOD FOR DETERMINING PRINT MEDIUM, AND METHOD FOR DETERMINING INK EJECTION AMOUNT CANON KABUSHIKI KAISHA (JP) 2007-09-06 US disclosed