Juarezic Acid

Juarezic Acid

SCHEMBL144680

O=C(O)/C=C\C=C\c1ccccc1

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 3/20 0.71
HDAC4 P56524 3/20 0.71
HDAC1 Q13547 3/20 0.71
HDAC2 Q92769 3/20 0.71
HDAC8 Q9BY41 3/20 0.71
HDAC6 Q9UBN7 3/20 0.71
HDAC7 Q8WUI4 2/20 0.71
HDAC10 Q969S8 2/20 0.71
HDAC11 Q96DB2 2/20 0.71
HDAC9 Q9UKV0 2/20 0.71
HDAC5 Q9UQL6 2/20 0.71
TNKS O95271 1/20 0.71
HCAR2 Q8TDS4 1/20 0.71
TNKS2 Q9H2K2 1/20 0.71
MAOB P27338 8/20 0.64
ALDH1A1 P00352 3/20 0.58
MAPT P10636 3/20 0.58
LMNA P02545 3/20 0.58
CYP1A2 P05177 2/20 0.58
CYP2D6 P10635 2/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Juarezic Acid SCHEMBL15119 1.00 HDAC3 (0.71) HDAC3HDAC4HDAC1HDAC2HDAC8
Juarezic Acid SCHEMBL436113 1.00 HDAC3 (0.71) HDAC3HDAC4HDAC1HDAC2HDAC8
Juarezic Acid SCHEMBL144681 1.00 HDAC3 (0.71) HDAC3HDAC4HDAC1HDAC2HDAC8
Juarezic Acid SCHEMBL11522747 1.00 HDAC3 (0.71) HDAC3HDAC4HDAC1HDAC2HDAC8
Juarezic Acid SCHEMBL474728 1.00 HDAC3 (0.71) HDAC3HDAC4HDAC1HDAC2HDAC8
Juarezic Acid SCHEMBL560728 0.98 HDAC3 (0.68) HDAC3HDAC4HDAC1HDAC2HDAC8
Juarezic Acid SCHEMBL30239689 0.98 HDAC3 (0.68) HDAC3HDAC4HDAC1HDAC2HDAC8
Juarezic Acid SCHEMBL3280210 0.98 HDAC3 (0.68) HDAC3HDAC4HDAC1HDAC2HDAC8
Juarezic Acid SCHEMBL2335383 0.98 HDAC3 (0.68) HDAC3HDAC4HDAC1HDAC2HDAC8
Juarezic Acid SCHEMBL5399197 0.98 HDAC3 (0.68) HDAC3HDAC4HDAC1HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 337 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8389713-B2 Polysaccharide pseudo-sponge SEIKAGAKU CORPORATION (JP) 2013-03-05 US claimed
US-20120055780-A1 POLYSACCHARIDE PSEUDO-SPONGE SEIKAGAKU CORPORATION (JP) 2012-03-08 US claimed
EP-2287205-A2 Photoreactive polysaccharide. photocrosslinked polysaccharide products, the method of making them and medical materials made therefrom SEIKAGAKU CORPORATION (JP) 2011-02-23 EP claimed
EP-1794192-A1 PHOTOREACTIVE POLYSACCHARIDE. PHOTOCROSSLINKED POLYSACCHARIDE PRODUCTS, THE METHOD OF MAKING THEM AND MEDICAL MATERIALS MADE THEREFROM SEIKAGAKU CORPORATION (JP) 2007-06-13 EP claimed
WO-2006030965-A1 PHOTOREACTIVE POLYSACCHARIDE, PHOTOCROSSLINKED POLYSACCHARIDE PRODUCTS, THE METHOD OF MAKING THEM AND MEDICAL MATERIALS THEREFROM SEIKAGAKU CORPORATION (JP) 2006-03-23 WO claimed
US-20060057098-A1 PHOTOREACTIVE POLYSACCHARIDE, PHOTOCROSSLINKED POLYSACCHARIDE PRODUCT AND METHOD OF MAKING SAME AND MEDICAL MATERIALS MADE FROM THE CROSSLINKED POLYSACCHARIDE SEIKAGAKU CORPORATION (JP) 2006-03-16 US claimed
US-5376503-A A photo-crosslinkable blends consisting of an isoolefin, a para-alkylstyrene and a photoinitiator substituted on the alkyl group of para-alkylstyrene monomers; corrosion, solvent resistance EXXON CHEMICAL PATENTS INC. (US) 1994-12-27 US claimed
EP-0563271-A1 UV/EB CURABLE BUTYL COPOLYMERS FOR COATING APPLICATIONS EXXON CHEMICAL PATENTS INC. (US) 1993-10-06 EP claimed
EP-0563251-A1 UV/EB CURABLE BUTYL COPOLYMERS FOR LITHOGRAPHIC AND CORROSION-RESISTANT COATING APPLICATIONS EXXON CHEMICAL PATENTS INC. (US) 1993-10-06 EP claimed
WO-1992011295-A1 UV/EB CURABLE BUTYL COPOLYMERS FOR COATING APPLICATIONS EXXON CHEMICAL PATENTS INC. (US) 1992-07-09 WO claimed
WO-1992011322-A2 UV/EB CURABLE BUTYL COPOLYMERS FOR LITHOGRAPHIC AND CORROSION-RESISTANT COATING APPLICATIONS EXXON CHEMICAL PATENTS INC. (US) 1992-07-09 WO claimed
EP-0179921-B1 BASE MATERIAL HAVING A DYED SURFACE FILM AND DYEING METHOD NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1990-08-08 EP claimed
JP-57189885-A None JP disclosed
JP-56110931-A None JP disclosed
JP-56022429-A None JP disclosed
JP-56122030-A None JP disclosed
US-4252879-A Image recording material having optically different particles DAI NIPPON INSATSU KABUSHIKI KAISHA (JP) 1981-02-24 US disclosed
US-4065430-A Functional group containing polymer and method of preparing the same FUJI PHOTO FILM CO., LTD. (JA) 1977-12-27 US disclosed
US-3950171-A THERMOPLASTIC RESIN DIAZONIUM SALT MITA INDUSTRIAL CO. LTD. (JA) 1976-04-13 US disclosed
US-3933885-A Cinnamylideneacetic acid esters FUJI PHOTO FILM CO., LTD. (JA) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060057098-A1 PHOTOREACTIVE POLYSACCHARIDE, PHOTOCROSSLINKED POLYSACCHARIDE PRODUCT AND METHOD OF MAKING SAME AND MEDICAL MATERIALS MADE FROM THE CROSSLINKED POLYSACCHARIDE ALG1, ALG8, CSGALNACT1 HDAC3 2682/4885HDAC4 1995/4885HDAC1 2778/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.