SCHEMBL3276100

SCHEMBL3276100

Oc1ccc(-c2cc(O)ccc2-c2ccccc2)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.68
MMP3 P08254 1/20 0.61
BCL2L1 Q07817 1/20 0.61
ESR2 Q92731 6/20 0.61
ESR1 P03372 6/20 0.59
ABL1 P00519 2/20 0.59
ABCB1 P08183 2/20 0.59
BCR P11274 2/20 0.59
HSD17B10 Q99714 1/20 0.53
BACE1 P56817 1/20 0.52
HSD17B1 P14061 1/20 0.52
HSD17B2 P37059 1/20 0.52
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
USP7 Q93009 1/20 0.49
POLB P06746 1/20 0.49
HTT P42858 1/20 0.49
RAB9A P51151 1/20 0.49
PELI1 Q96FA3 1/20 0.49
NTSR1 P30989 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8450699 1.00 ALOX5 (0.68) ALOX5MMP3BCL2L1ESR2ESR1
SCHEMBL27831218 0.98 ALOX5 (0.65) ALOX5MMP3BCL2L1ESR2ESR1
SCHEMBL3802935 0.95 ALOX5 (0.74) ALOX5MMP3BCL2L1ESR2ESR1
Hydrogen Sulfide SCHEMBL27798330 0.93 ALOX5 (0.71) ALOX5MMP3BCL2L1ESR2ESR1
Phosphine SCHEMBL28090181 0.93 ALOX5 (0.71) ALOX5MMP3BCL2L1ESR2ESR1
SCHEMBL29786722 0.91 ALOX5 (0.63) ALOX5MMP3BCL2L1ESR2ESR1
Ethane SCHEMBL6838808 0.91 ALOX5 (0.68) ALOX5MMP3BCL2L1ESR2ESR1
SCHEMBL503746 0.91 ALOX5 (0.74) ALOX5MMP3BCL2L1ESR2ESR1
SCHEMBL5523942 0.89 MMP3 (0.65) ALOX5MMP3BCL2L1ESR2ESR1
SCHEMBL16581499 0.89 MMP3 (0.65) ALOX5MMP3BCL2L1ESR2ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5049642-A Polyethers, polythioethers IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-09-17 US claimed
US-5008472-A Preparation of 4,4\"-dihydroxyterphenyl BASF AKTIENGESELLSCHAFT (DE) 1991-04-16 US claimed
JP-5331255-A None JP disclosed
JP-6239980-A None JP disclosed
EP-3215487-A1 POLYARYLENE ETHER SULFONE (PAES) POLYMERS AND METHODS FOR MAKING THE SAME Solvay Specialty Polymers USA, LLC. (US) 2017-09-13 EP disclosed
US-20170073287-A1 PROCESS FOR THE MANUFACTURE OF TERPHENYL COMPOUNDS SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2017-03-16 US disclosed
EP-3131868-A1 Process for the manufacture of terphenyl compounds Solvay Specialty Polymers USA, L.L.C. (US) 2017-02-22 EP disclosed
US-20170036978-A1 PROCESS FOR THE MANUFACTURE OF TERPHENYL COMPOUNDS SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2017-02-09 US disclosed
EP-3116846-A1 PROCESS FOR THE MANUFACTURE OF TERPHENYL COMPOUNDS Solvay Specialty Polymers USA, LLC. (US) 2017-01-18 EP disclosed
EP-3097136-A1 NEW POLYMERIC MATERIALS Solvay Specialty Polymers USA, L.L.C. (US) 2016-11-30 EP disclosed
WO-2016071088-A1 POLYARYLENE ETHER SULFONE (PAES) POLYMERS AND METHODS FOR MAKING THE SAME SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2016-05-12 WO disclosed
US-5049642-A Polyethers, polythioethers IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-09-17 US disclosed
US-5008334-A Blend of epoxy/diol copolymer and an addition/condensation block polymer of the epoxy/diol and epoxy-capped, carboxylated butadiene; impact, chip and corrosion resistant, electro depositable car primers BASF CORPORATION (US) 1991-04-16 US disclosed
US-5008472-A Preparation of 4,4\"-dihydroxyterphenyl BASF AKTIENGESELLSCHAFT (DE) 1991-04-16 US disclosed
US-5008472-A Preparation of 4,4\"-dihydroxyterphenyl BASF AKTIENGESELLSCHAFT (DE) 1991-04-16 US disclosed
EP-0416082-A1 MIXTURE OF EPOXY/DIOL COPOLYMER AND EPOXY/DIOL COPOLYMER//EPOXY-CAPPED POLYBUTADIENE BLOCK COPOLYMER BASF Corporation (US) 1991-03-13 EP disclosed
WO-1990010034-A1 MIXTURE OF EPOXY/DIOL COPOLYMER AND EPOXY/DIOL COPOLYMER//EPOXY-CAPPED POLYBUTADIENE BLOCK COPOLYMER BASF CORPORATION (US) 1990-09-07 WO disclosed
EP-0375287-A2 Aromatic polymers NORTH WEST WATER GROUP PLC (GB) 1990-06-27 EP disclosed
EP-0360092-A1 Process for preparing 4,4\"-dihydroxyterphenyl BASF Aktiengesellschaft (DE) 1990-03-28 EP disclosed
EP-0360092-A1 Process for preparing 4,4\"-dihydroxyterphenyl BASF Aktiengesellschaft (DE) 1990-03-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170036978-A1 PROCESS FOR THE MANUFACTURE OF TERPHENYL COMPOUNDS ALK, PIK3C3, ITK ALOX5 2661/4885MMP3 4625/4885BCL2L1 4532/4885
US-20170073287-A1 PROCESS FOR THE MANUFACTURE OF TERPHENYL COMPOUNDS C9, C5, TECR ALOX5 286/4885MMP3 4701/4885BCL2L1 3319/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.